Introduction
Lizospey is a medication that contains the active ingredient Linezolid. It is available in the form of an oral suspension and is commonly prescribed under the brand name Lizospey.
Uses
Lizospey is primarily used to treat certain types of bacterial infections. It is commonly prescribed for skin and soft tissue infections caused by susceptible bacteria, including methicillin-resistant Staphylococcus aureus (MRSA).
Dosage and Administration
The dosage of Lizospey will vary depending on the specific infection being treated, the severity of the infection, and the patient’s age and weight. Follow the instructions provided by your healthcare professional.
Generally, the recommended dosage for adults and children over the age of 12 is 600 mg (10 mL) of Lizospey every 12 hours. For children between the ages of 5 and 12, the recommended dosage is 10 mg/kg (up to a maximum of 600 mg) every 12 hours. For children under 5 years of age, the dosage should be determined by the healthcare professional based on the child’s weight.
Lizospey should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal. Shake the suspension well before each use and use the provided measuring device to accurately measure the dose.
Mechanism of Action
Lizospey belongs to a class of medications called oxazolidinones. It works by inhibiting the growth of bacteria, specifically by preventing the production of proteins that are essential for bacterial growth. By interfering with protein synthesis, Lizospey helps to stop the spread of the infection and allows the body’s immune system to effectively fight off the bacteria.
Side Effects
Common side effects may include nausea, vomiting, diarrhea, headache, and dizziness. These side effects are usually mild and go away on their own.
However, there are some potentially serious side effects associated with Lizospey. If you experience any of the following symptoms, seek medical attention immediately: severe diarrhea, persistent headache, vision changes, easy bruising or bleeding, unusual tiredness, signs of an allergic reaction (such as rash, itching, swelling, severe dizziness, or trouble breathing), or signs of a condition called serotonin syndrome (such as agitation, hallucinations, fast heartbeat, fever, muscle stiffness, or twitching).
Drug Interactions
inform your healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Certain medications may interact with Lizospey and affect its effectiveness or increase the risk of side effects.
Some medications that may interact with Lizospey include certain antidepressants (such as selective serotonin reuptake inhibitors), certain migraine medications (such as triptans), certain cough and cold medications (such as dextromethorphan), and certain drugs that increase serotonin levels (such as tramadol).
Precautions
Before taking Lizospey, inform your healthcare professional about any allergies you may have, as well as any medical conditions you have, such as liver disease, kidney disease, or a history of high blood pressure.
Lizospey should not be used in combination with certain medications, such as monoamine oxidase inhibitors (MAOIs) or certain serotonergic medications, as this may increase the risk of a serious condition called serotonin syndrome.
Storage
Lizospey should be stored at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed when not in use. Do not freeze the medication.
Patient Tips
- Take Lizospey exactly as prescribed by your healthcare professional. Do not skip doses or stop taking the medication without consulting your healthcare professional.
- complete the full course of treatment, even if you start feeling better before the medication is finished.
- If you experience severe or persistent diarrhea while taking Lizospey, inform your healthcare professional, as this may be a sign of a more serious infection.
- Avoid consuming alcoholic beverages while taking Lizospey, as it may increase the risk of certain side effects.
- If you have any questions or concerns about Lizospey, consult your healthcare professional for further guidance.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Linezolid 2 mg/ml solution for infusion (Health Professionals SmPC) Available at:
- Linezolid oral/injection (Drugs.com) [Accessed 18 Jun. 2024] (online) Available at:
- linezolid (RX) [Accessed 5 Jun. 2024] (online) Available at:
- Linezolid (MedlinePlus) [Accessed 10 Jun. 2024] (online) Available at:
- Conradie F, Bagdasaryan TR, Borisov S, Howell P, Mikiashvili L, Ngubane N, Samoilova A, Skornykova S, Tudor E, Variava E, Yablonskiy P, Everitt D, Wills GH, Sun E, Olugbosi M, Egizi E, Li M, Holsta A, Timm J, Bateson A, Crook AM, Fabiane SM, Hunt R, McHugh TD, Tweed CD, Foraida S, Mendel CM, Spigelman M; ZeNix Trial Team. Bedaquiline-Pretomanid-Linezolid Regimens for Drug-Resistant Tuberculosis. N Engl J Med. 2022 Sep 1;387(9):810-823. doi: 10.1056/NEJMoa2119430. [Accessed 22 Jun. 2024] Available at:
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