Macirol 10mg Tablet

Introduction

Macirol is a prescription medication that contains the active ingredient Macitentan. It is available under the brand name Macirol. This medication is primarily used for the treatment of pulmonary arterial hypertension (PAH).

Uses

Macirol is prescribed to manage pulmonary arterial hypertension (PAH) in adults. PAH is a condition characterized by high blood pressure in the arteries that carry blood from the heart to the lungs. Macirol helps to relax and widen the blood vessels in the lungs, reducing the pressure and improving blood flow.

Dosage and Administration

The dosage of Macirol will vary depending on the individual’s condition and response to treatment. Follow the instructions provided by your healthcare professional. The tablets should be taken orally, with or without food, once daily. Swallow the tablet whole, without crushing or chewing it.

Mechanism of Action

Macirol contains Macitentan, which belongs to a class of medications known as endothelin receptor antagonists. It works by blocking the action of endothelin, a substance in the body that causes blood vessels to constrict. By blocking the effects of endothelin, Macirol helps to relax and widen the blood vessels in the lungs, improving blood flow and reducing the strain on the heart.

Side Effects

Common side effects may include headache, nasal congestion, cough, and swelling in the ankles or legs. These side effects are usually mild and go away on their own. However, if you experience any severe or persistent side effects, such as chest pain, shortness of breath, or signs of liver problems (such as yellowing of the skin or eyes), seek medical attention immediately.

Drug Interactions

Macirol may interact with certain medications, including anticoagulants (blood thinners), cyclosporine, and rifampin. Inform your healthcare professional about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. They can determine if any adjustments need to be made to your treatment plan to avoid potential drug interactions.

Precautions

Before taking Macirol, discuss your medical history and any pre-existing conditions with your healthcare professional. Inform them if you have liver problems, kidney problems, or if you are pregnant or breastfeeding. Macirol may not be suitable for everyone, and your healthcare professional will assess the potential risks and benefits before prescribing this medication.

Storage

Macirol should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Follow the dosage instructions provided by your healthcare professional.
• take Macirol at the same time each day to maintain a consistent level of the medication in your body.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not stop taking Macirol without consulting your healthcare professional, as this may worsen your condition.
• If you have any questions or concerns about your treatment, speak to your healthcare professional for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Macitentan (Drugs.com) [Accessed 27 Jun. 2024] (online) Available at:
• macitentan 10 mg-tadalafil 20 mg tablet (RX) [Accessed 14 Jun. 2024] (online) Available at:
• Macitentan and Tadalafil (MedlinePlus) [Accessed 21 Jun. 2024] (online) Available at:
• Pulido T, Adzerikho I, Channick RN, Delcroix M, Galiè N, Ghofrani HA, Jansa P, Jing ZC, Le Brun FO, Mehta S, Mittelholzer CM, Perchenet L, Sastry BK, Sitbon O, Souza R, Torbicki A, Zeng X, Rubin LJ, Simonneau G; SERAPHIN Investigators. Macitentan and morbidity and mortality in pulmonary arterial hypertension. N Engl J Med. 2013 Aug 29;369(9):809-18. doi: 10.1056/NEJMoa1213917. [Accessed 27 Jun. 2024] Available at: