Makled-RO Tablet

Introduction

Makled-RO is a prescription medication that contains two active ingredients: Ondansetron and Rabeprazole. It is available in tablet form and is commonly prescribed by healthcare professionals.

Uses

Makled-RO is used to treat various conditions related to the digestive system. It is primarily prescribed to manage symptoms of nausea and vomiting caused by chemotherapy, radiation therapy, or surgery. Additionally, it is also used to treat symptoms of gastroesophageal reflux disease (GERD) such as heartburn and acid reflux.

Dosage and Administration

The dosage of Makled-RO may vary depending on the specific medical condition being treated and individual patient factors. Follow the dosage instructions provided by your healthcare professional. Typically, the recommended dose for adults is one tablet taken orally before meals, usually once a day. However, your doctor may adjust the dosage based on your response to the medication.

Mechanism of Action

Makled-RO works by targeting specific receptors in the body. Ondansetron blocks the action of serotonin, a neurotransmitter involved in triggering nausea and vomiting. By blocking these receptors, it helps to reduce these symptoms. Rabeprazole, the other active ingredient, belongs to a class of medications known as proton pump inhibitors. It works by reducing the production of acid in the stomach, providing relief from symptoms of acid reflux and GERD.

Side Effects

Common side effects may include headache, constipation, diarrhea, and dizziness. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, consult your healthcare professional.

In rare cases, Makled-RO may cause more serious side effects. These can include allergic reactions, severe stomach pain, difficulty breathing, and irregular heartbeat. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Makled-RO may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. Inform your healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some common medications that may interact with Makled-RO include certain antidepressants, anticoagulants, and medications that affect liver enzymes. Your doctor will consider these potential interactions when prescribing Makled-RO.

Precautions

Before taking Makled-RO, inform your healthcare professional about any allergies you may have, especially to Ondansetron, Rabeprazole, or any other medications. Additionally, inform your doctor about any other medical conditions you have, such as liver disease or heart problems.

Avoid consuming alcohol while taking Makled-RO, as it may increase the risk of side effects.

Storage

Makled-RO should be stored in a cool, dry place, away from direct sunlight and moisture. Keep it out of the reach of children and pets. Do not use Makled-RO after the expiration date printed on the packaging.

Patient Tips

• Take Makled-RO exactly as prescribed by your healthcare professional. Do not take more or less than the recommended dose.
• If you are taking Makled-RO for chemotherapy or radiation-induced nausea and vomiting, it is usually taken 30 minutes before the start of treatment.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• If you have any concerns or questions about Makled-RO, consult your healthcare professional for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Rabeprazole: medicine to lower stomach acid (NHS UK) [Accessed 30 Jun. 2024] (online) Available at:
• Ondansetron 2 mg/ml Solution for Injection (Health Professionals SmPC) Available at:
• Ondansetron (Drugs.com) [Accessed 3 Jun. 2024] (online) Available at:
• ondansetron (pf) in dextrose piggyback (RX) [Accessed 19 Jun. 2024] (online) Available at:
• Ondansetron Injection (MedlinePlus) [Accessed 2 Jun. 2024] (online) Available at:
• Roila F, Del Favero A. Ondansetron clinical pharmacokinetics. Clin Pharmacokinet. 1995 Aug;29(2):95-109. doi: 10.2165/00003088-199529020-00004. [Accessed 15 Jun. 2024] Available at: