Makoril DS Oral Suspension

Introduction

Makoril DS is a prescription medication that contains a combination of active ingredients including Paracetamol, Chlorpheniramine Maleate, Phenylephrine, Sodium Citrate, Ammonium Chloride, and Menthol. It is available in the form of an oral suspension and is commonly used to relieve symptoms associated with the common cold, flu, and allergies.

Uses

Makoril DS is primarily prescribed to alleviate symptoms such as fever, headache, body aches, nasal congestion, sneezing, and sore throat that are often experienced during colds, flu, and allergies. It provides temporary relief and helps improve overall comfort.

Dosage and Administration

follow the dosage instructions provided by your healthcare professional or as indicated on the product packaging. The recommended dosage for adults and children over 12 years of age is 10 ml of Makoril DS every 4-6 hours, up to a maximum of 4 doses in a 24-hour period. For children aged 6-12 years, the recommended dosage is 5 ml every 4-6 hours, up to a maximum of 4 doses in a 24-hour period.

Shake the bottle well before use. Use the provided measuring cup or syringe to ensure accurate dosing. Do not exceed the recommended dosage unless directed by your healthcare professional.

Mechanism of Action

Makoril DS works by combining the effects of its active ingredients to provide relief from symptoms. Paracetamol is a pain reliever and fever reducer, Chlorpheniramine Maleate is an antihistamine that helps reduce sneezing and itching, Phenylephrine is a nasal decongestant that helps relieve nasal congestion, Sodium Citrate and Ammonium Chloride help relieve cough, and Menthol provides a cooling effect to soothe throat irritation.

Side Effects

Common side effects may include drowsiness, dry mouth, dizziness, and upset stomach. These side effects are usually mild and temporary.

Serious side effects are rare but may include severe allergic reactions, difficulty breathing, rapid heartbeat, confusion, and hallucinations. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

inform your healthcare professional about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. Makoril DS may interact with certain medications, such as monoamine oxidase inhibitors (MAOIs), antidepressants, and medications that can cause drowsiness. These interactions can potentially increase the risk of side effects or reduce the effectiveness of the medications. Always consult your healthcare professional before starting or stopping any medication.

Precautions

Before using Makoril DS, inform your healthcare professional if you have any existing medical conditions, such as liver disease, kidney disease, high blood pressure, diabetes, or thyroid problems. Take precautions if you are pregnant, breastfeeding, or planning to become pregnant.

Avoid consuming alcohol while taking Makoril DS, as it may increase the risk of side effects such as drowsiness and dizziness. Additionally, do not take more than the recommended dosage to avoid potential complications.

Storage

Store Makoril DS in a cool, dry place, away from direct sunlight and out of the reach of children. Do not freeze the medication. Proper storage helps maintain the effectiveness and safety of the product.

Patient Tips

• Follow the dosage instructions provided by your healthcare professional or as indicated on the product packaging.
• Use the provided measuring cup or syringe to ensure accurate dosing.
• If symptoms persist or worsen after a few days of using Makoril DS, consult your healthcare professional.
• Stay well-hydrated by drinking plenty of fluids while using this medication.
• Avoid driving or operating heavy machinery if you experience drowsiness or dizziness.
• If you have any questions or concerns about Makoril DS, consult your healthcare professional for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Vitamins and minerals – Others (NHS UK) [Accessed 18 Jun. 2024] (online) Available at:
• Beechams Breathe Clear Hot Honey & Lemon Menthol Flavour Powder for Oral Solution (Health Professionals SmPC) Available at:
• Ammonium Chloride (Drugs.com) [Accessed 16 Jun. 2024] (online) Available at:
• chlorpheniramine maleate (OTC) [Accessed 11 Jun. 2024] (online) Available at:
• Acid loading test (pH) [Accessed 16 Jun. 2024] (online) Available at:
• [No authors listed] Ammonium chloride acidosis. Br Med J. 1961 Aug 12;2(5249):441. [Accessed 3 Jun. 2024] Available at: