Manaderm Tablet

Introduction

Manaderm is a prescription medication that contains the active ingredient Psoralen. It is also available under its generic name. This medication is primarily used for the treatment of certain skin conditions, specifically psoriasis and vitiligo.

Uses

Manaderm is prescribed to patients who have been diagnosed with psoriasis or vitiligo. Psoriasis is a chronic autoimmune skin condition that causes red, scaly patches on the skin, while vitiligo is a long-term skin disorder characterized by the loss of skin color in patches.

Dosage and Administration

The dosage of Manaderm will depend on various factors, including the severity of the condition and the individual patient’s response to the medication. Follow the instructions provided by your healthcare professional or as indicated on the prescription label.

Typically, Manaderm is taken orally with or without food. It is usually recommended to take it with a meal to minimize stomach upset. Swallow the tablet whole and not crush, chew, or break it.

Mechanism of Action

Manaderm works by affecting the way certain cells in the skin respond to ultraviolet (UV) light. It belongs to a class of medications known as psoralens. When exposed to UV light, psoralens help to normalize the growth of skin cells and reduce inflammation, which can alleviate the symptoms of psoriasis and vitiligo.

Side Effects

Common side effects may include nausea, dizziness, headache, and skin irritation. These side effects are usually mild and temporary.

However, be aware of more serious side effects that may occur, although they are rare. These can include severe allergic reactions, changes in vision, or an increased sensitivity to sunlight. If you experience any of these serious side effects, seek medical attention immediately.

Drug Interactions

Manaderm may interact with certain medications or substances, which can affect its effectiveness or increase the risk of side effects. Inform your healthcare professional about all the medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins.

Some medications that may interact with Manaderm include certain antibiotics, antidepressants, and antifungal medications. Additionally, certain substances such as grapefruit juice and tobacco may also interact with this medication. Discuss potential drug interactions with your healthcare professional.

Precautions

Before taking Manaderm, inform your healthcare professional about any medical conditions you have, including liver or kidney disease, heart problems, or a history of skin cancer. This medication may not be suitable for everyone, and your healthcare professional will determine if it is appropriate for you.

Manaderm should not be used by pregnant or breastfeeding women, as it may potentially harm the fetus or infant. Discuss the potential risks and benefits with your healthcare professional if you are pregnant, planning to become pregnant, or breastfeeding.

Storage

Manaderm should be stored at room temperature, away from moisture and heat. Keep this medication out of the reach of children and pets. Do not use this medication if it has expired or if the tablets are discolored or damaged.

Patient Tips

• follow the prescribed dosage and administration instructions provided by your healthcare professional.
• Avoid excessive exposure to sunlight or artificial UV light while taking Manaderm, as it may increase the risk of skin damage.
• If you experience any new or worsening symptoms while taking this medication, contact your healthcare professional.
• Inform your healthcare professional about any other medications or substances you are taking to avoid potential drug interactions.
• If you have any concerns or questions about Manaderm, do not hesitate to reach out to your healthcare professional for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Mastocytosis – Treatment (NHS UK) [Accessed 19 Jun. 2024] (online) Available at:
• Methoxsalen Disease Interactions (Drugs.com) [Accessed 23 Jun. 2024] (online) Available at:
• General Information about Mycosis Fungoides (Including Sézary Syndrome) (National Cancer Institute) [Accessed 4 Jun. 2024] (online) Available at:
• Ellis CR, Elston DM. Psoralen-Induced Phytophotodermatitis. Dermatitis. 2021 May-Jun 01;32(3):140-143. doi: 10.1097/DER.0000000000000691. [Accessed 6 Jun. 2024] Available at: