Manilup 20% Infusion

Introduction

Manilup is a prescription medication that contains Mannitol as its active ingredient. It is available in the form of an infusion.

Uses

Manilup is primarily used to treat certain conditions that involve an excessive buildup of fluids in the body, such as cerebral edema (swelling of the brain) and acute kidney injury. It helps to reduce fluid accumulation and promote the removal of excess fluids from the body.

Dosage and Administration

The dosage and administration of Manilup should be determined by a healthcare professional, as it depends on various factors such as the patient’s age, weight, and the specific condition being treated. It is typically administered intravenously (into a vein) under the supervision of a healthcare provider. The infusion rate and duration will also be determined by the healthcare professional.

Mechanism of Action

Mannitol, the active ingredient in Manilup, works by increasing the osmotic pressure in the kidneys and brain. This helps to draw excess fluid out of the tissues and into the bloodstream, where it can be eliminated by the body. By reducing fluid accumulation, Mannitol helps to alleviate the symptoms associated with conditions such as cerebral edema and acute kidney injury.

Side Effects

Common side effects may include headache, dizziness, nausea, vomiting, and increased urination. These side effects are usually mild and temporary.

However, be aware of any serious side effects that may occur. These can include severe allergic reactions, difficulty breathing, chest pain, irregular heartbeat, and changes in urine output. If any of these serious side effects occur, seek immediate medical attention.

Drug Interactions

Manilup may interact with certain medications, including diuretics, lithium, and other medications that affect kidney function. Inform your healthcare provider about all the medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. They can determine whether any potential drug interactions may occur and adjust your treatment accordingly.

Precautions

Before using Manilup, inform your healthcare provider about any medical conditions you have, especially if you have a history of heart disease, kidney problems, or electrolyte imbalances. This medication may not be suitable for everyone, and your healthcare provider will consider these factors before prescribing it.

Manilup should not be used in patients who are allergic to Mannitol or any other ingredients in the formulation. Read the medication’s label and consult with your healthcare provider if you have any concerns or questions.

Storage

Manilup should be stored as directed by your healthcare provider or as indicated on the packaging. It is typically stored in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets.

Patient Tips

• Follow the dosage instructions provided by your healthcare provider.
• If you experience any unusual or bothersome side effects, contact your healthcare provider.
• Be sure to inform your healthcare provider about all the medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins.
• Store the medication properly according to the instructions provided.
• If you have any questions or concerns about Manilup, don’t hesitate to reach out to your healthcare provider for clarification.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Bortezomib 1mg powder for solution for injection (Health Professionals SmPC) Available at:
• Mannitol injection (Drugs.com) [Accessed 16 Jun. 2024] (online) Available at:
• mannitol 40 mg inhalation powder in a capsule (RX) [Accessed 22 Jun. 2024] (online) Available at:
• Drug Development Pipeline (Cystic Fibrosis Foundation) [Accessed 6 Jun. 2024] (online) Available at:
• Chen M, Zhang W, Wu H, Guang C, Mu W. Mannitol: physiological functionalities, determination methods, biotechnological production, and applications. Appl Microbiol Biotechnol. 2020 Aug;104(16):6941-6951. doi: 10.1007/s00253-020-10757-y. Epub 2020 Jun 29. [Accessed 19 Jun. 2024] Available at: