Maniplus Infusion

Introduction

Maniplus is a prescription medication that contains the active ingredients Glycerin and Mannitol. It is available in an infusion form and is primarily used for specific medical conditions.

Uses

Maniplus is prescribed by healthcare professionals to treat certain conditions. It is commonly used to help reduce brain swelling and intracranial pressure in patients who have suffered from traumatic brain injury, cerebral edema, or stroke. It may also be used during surgical procedures to maintain proper hydration.

Dosage and Administration

The dosage of Maniplus will be determined by your healthcare provider based on your specific medical condition, age, and other factors. It is usually administered intravenously (IV) by a healthcare professional in a hospital or clinical setting. The infusion rate and duration will be carefully monitored and adjusted as needed.

Mechanism of Action

Maniplus works by drawing excess fluid out of the tissues in the body, including the brain. Glycerin and Mannitol exert an osmotic effect, meaning they create a pressure gradient that helps remove fluid from swollen tissues. This action helps to reduce brain swelling and intracranial pressure, allowing for improved blood flow and oxygenation.

Side Effects

Common side effects may include headache, nausea, vomiting, and fluid and electrolyte imbalances. If you experience any of these side effects or any other unusual symptoms, notify your healthcare provider immediately.

In rare cases, serious side effects may occur. These may include allergic reactions, changes in heart rhythm, and kidney problems. If you experience any severe or persistent side effects, seek medical attention right away.

Drug Interactions

inform your healthcare provider about all the medications you are currently taking, including prescription and over-the-counter drugs, as well as any herbal supplements or vitamins. Certain medications may interact with Maniplus and affect its effectiveness or increase the risk of side effects. Your healthcare provider will carefully consider these potential interactions and adjust your treatment plan accordingly.

Precautions

Before starting treatment with Maniplus, inform your healthcare provider about any medical conditions you have, especially if you have a history of heart problems, kidney disease, or dehydration. Additionally, let your healthcare provider know about any allergies or sensitivities you may have to medications.

Maniplus is contraindicated in patients who are hypersensitive to Glycerin, Mannitol, or any other ingredients in the medication. It should not be used in patients with severe dehydration or other serious medical conditions without proper medical supervision.

Storage

Patient Tips

• follow the dosage instructions provided by your healthcare provider and not to exceed the prescribed amount.
• During the infusion, you will be closely monitored by healthcare professionals to ensure your safety and response to the medication.
• If you have any concerns or questions about the medication or its administration, do not hesitate to ask your healthcare provider or pharmacist for clarification.
• Keep all follow-up appointments with your healthcare provider to monitor your progress and assess the effectiveness of the treatment.
• If you miss a scheduled dose of Maniplus, contact your healthcare provider for further instructions.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Glyceryl trinitrate (GTN): a medicine for angina and anal fissures (NHS UK) [Accessed 19 Jun. 2024] (online) Available at:
• Boots Calamine and Glycerin Cream (Health Professionals SmPC) Available at:
• Glycerin rectal (Drugs.com) [Accessed 12 Jun. 2024] (online) Available at:
• adult glycerin 3 g rectal suppository (OTC) [Accessed 26 Jun. 2024] (online) Available at:
• Medications and Supplements (Other Than Steroids) (Parent Project for Muscular Dystrophy Research) [Accessed 7 Jun. 2024] (online) Available at:
• Becker LC, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Gill LJ, Heldreth B. Safety Assessment of Glycerin as Used in Cosmetics. Int J Toxicol. 2019 Nov/Dec;38(3_suppl):6S-22S. doi: 10.1177/1091581819883820. [Accessed 16 Jun. 2024] Available at: