MEFDATE 250MG/250MG TABLET

Introduction

MEFDATE is a prescription medication that contains two active ingredients: Ethamsylate and Mefenamic Acid. It is commonly used to treat conditions associated with excessive bleeding, such as heavy menstrual bleeding, nosebleeds, and bleeding after dental procedures or surgery.

Uses

MEFDATE is primarily prescribed for the following conditions:

• Heavy menstrual bleeding (menorrhagia)
• Nosebleeds (epistaxis)
• Bleeding after dental procedures or surgery

Dosage and Administration

The recommended dosage of MEFDATE may vary depending on the severity of the condition being treated and individual patient factors. Follow the instructions provided by your healthcare professional.

Typically, the usual dosage for adults is one tablet taken three times a day, with or after meals. The duration of treatment will be determined by your healthcare professional based on your specific needs.

Take MEFDATE exactly as prescribed and not to exceed the recommended dosage.

Mechanism of Action

MEFDATE contains two active ingredients: Ethamsylate and Mefenamic Acid.

• Ethamsylate works by helping to reduce bleeding by improving blood vessel tone and preventing the breakdown of blood clots.
• Mefenamic Acid is a nonsteroidal anti-inflammatory drug (NSAID) that helps to reduce pain, inflammation, and fever associated with excessive bleeding.

The combination of these two ingredients in MEFDATE provides a synergistic effect in managing excessive bleeding.

Side Effects

be aware of the potential side effects and to seek medical attention if they occur.

Common side effects of MEFDATE may include:

• Upset stomach
• Nausea
• Diarrhea
• Headache
• Dizziness

Serious side effects are rare but may include:

• Severe allergic reactions (rash, itching, swelling, difficulty breathing)
• Severe stomach pain or bleeding
• Black, tarry stools or blood in the urine
• Yellowing of the skin or eyes (jaundice)

If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

inform your healthcare professional about all the medications you are currently taking, including prescription, over-the-counter, and herbal products, before starting MEFDATE. This is because certain medications may interact with MEFDATE, potentially affecting its effectiveness or increasing the risk of side effects.

Common drug interactions may occur with:

• Anticoagulants (blood thinners)
• Antiplatelet drugs
• Nonsteroidal anti-inflammatory drugs (NSAIDs)
• Corticosteroids
• Certain antidepressants

discuss with your healthcare professional about potential drug interactions before starting MEFDATE.

Precautions

Before taking MEFDATE, inform your healthcare professional if you have any known allergies, medical conditions, or if you are currently pregnant or breastfeeding.

• MEFDATE should be used with caution in patients with a history of gastrointestinal disorders, kidney or liver problems, or asthma.
• follow your healthcare professional’s instructions and not to exceed the recommended dosage.
• MEFDATE should not be used in patients with a known hypersensitivity to Ethamsylate, Mefenamic Acid, or any other ingredients in the medication.
• Avoid alcohol consumption while taking MEFDATE, as it may increase the risk of stomach irritation and bleeding.

Storage

MEFDATE should be stored at room temperature, away from direct sunlight and moisture. Keep it out of the reach of children and pets. Do not use the medication if it has expired or shows any signs of tampering.

Patient Tips

• Take MEFDATE with or after meals to minimize the risk of stomach upset.
• If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not double the dose to make up for a missed one.
• If you have any concerns or questions about MEFDATE, do not hesitate to consult your healthcare professional for further guidance.
• attend regular follow-up appointments with your healthcare professional to monitor your progress and discuss any concerns or changes in your condition.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Isovaleric acidaemia (NHS UK) [Accessed 26 Jun. 2024] (online) Available at:
• Mefenamic Acid 250 mg Capsules (Health Professionals SmPC) Available at:
• Etamsylate (International database) (Drugs.com) [Accessed 21 Jun. 2024] (online) Available at:
• mefenamic acid (ponstel) (RX) [Accessed 22 Jun. 2024] (online) Available at:
• Mefenamic Acid (MedlinePlus) [Accessed 16 Jun. 2024] (online) Available at:
• Hunt R, Hey E. Ethamsylate for the prevention of morbidity and mortality in preterm or very low birth weight infants. Cochrane Database Syst Rev. 2010 Jan 20;(1):CD004343. doi: 10.1002/14651858.CD004343.pub2. [Accessed 28 Jun. 2024] Available at: