Mendate 15 Tablet CR

Introduction

Mendate is a medication that contains the active ingredient Norethisterone. It is available under the brand name Mendate. This medication is primarily used for certain hormonal conditions and as a contraceptive.

Uses

Mendate is prescribed for various conditions, including:

• Abnormal uterine bleeding: It can help regulate and reduce heavy or irregular menstrual bleeding.
• Endometriosis: It is used to manage the symptoms of endometriosis, a condition where the tissue lining the uterus grows outside the uterus.
• Contraception: Mendate can be used as a hormonal contraceptive to prevent pregnancy.

Dosage and Administration

The dosage and administration of Mendate may vary depending on the specific condition being treated. Follow the instructions provided by your healthcare professional. Generally, the recommended dosage is one tablet taken orally once a day, with or without food. Take the medication at the same time each day for maximum effectiveness.

Mechanism of Action

Mendate contains Norethisterone, which is a synthetic form of the hormone progesterone. It works by modifying the lining of the uterus, reducing the growth of the uterine lining, and regulating menstrual bleeding. Additionally, it suppresses the release of certain hormones involved in the menstrual cycle, preventing ovulation and thus acting as a contraceptive.

Side Effects

Common side effects may include nausea, headache, breast tenderness, mood changes, and changes in menstrual bleeding patterns. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, contact your healthcare professional.

In rare cases, Mendate may cause serious side effects such as blood clots, liver problems, or allergic reactions. Seek immediate medical attention if you experience symptoms such as severe abdominal pain, chest pain, shortness of breath, yellowing of the skin or eyes, or a severe allergic reaction.

Drug Interactions

Mendate may interact with certain medications, including:

• Anticoagulants: It may increase the risk of bleeding when used with medications like warfarin.
• Antiepileptic drugs: It may decrease the effectiveness of certain antiepileptic medications.
• Some antibiotics: It may reduce the effectiveness of antibiotics like rifampicin.

Inform your healthcare professional about all the medications you are taking, including prescription, over-the-counter, and herbal products, to avoid potential drug interactions.

Precautions

Before starting Mendate, discuss any medical conditions or allergies you have with your healthcare professional. They should be aware of your medical history, especially if you have a history of blood clots, liver problems, or certain cancers. This medication is not suitable for use during pregnancy, and use appropriate contraception while taking it.

Mendate may interact with other medications or substances, such as tobacco or alcohol. Avoid smoking and limit alcohol consumption while taking this medication.

Storage

Mendate should be stored at room temperature, away from moisture and heat. Keep it out of the reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Take Mendate exactly as prescribed by your healthcare professional.
• If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not stop taking the medication without consulting your healthcare professional, even if you start feeling better.
• If you are planning to become pregnant or have any concerns about using Mendate, discuss them with your healthcare professional.
• If you experience severe or persistent side effects, contact your healthcare professional for guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Brevinor Tablets (Health Professionals SmPC) Available at:
• NORETHISTERONE 5MG TABLETS (Drugs.com) [Accessed 1 Jun. 2024] (online) Available at:
• Norethindrone (MedlinePlus) [Accessed 6 Jun. 2024] (online) Available at:
• Huvinen E, Holopainen E, Heikinheimo O. Norethisterone and its acetate – what’s so special about them? BMJ Sex Reprod Health. 2021 Apr;47(2):102-109. doi: 10.1136/bmjsrh-2020-200619. Epub 2020 May 12. [Accessed 11 Jun. 2024] Available at: