Metagesic Plus Syrup

Introduction

Metagesic Plus is a medication that contains two active ingredients: Ibuprofen and Paracetamol. It is commonly used to relieve pain and reduce fever. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that helps reduce inflammation and relieve pain, while Paracetamol is an analgesic and antipyretic medication that helps reduce pain and fever.

Uses

Metagesic Plus is prescribed for the management of mild to moderate pain, such as headaches, toothaches, and menstrual cramps. It is also commonly used to reduce fever associated with various conditions, such as colds, flu, and other viral or bacterial infections.

Dosage and Administration

The recommended dosage of Metagesic Plus for adults and children over 12 years of age is 10 ml every 6 to 8 hours, as needed for pain or fever. The maximum daily dose should not exceed 40 ml. For children aged 6 to 12 years, the recommended dosage is 5 ml every 6 to 8 hours, with a maximum daily dose of 20 ml. Follow the dosing instructions provided by your healthcare professional or as indicated on the packaging.

Metagesic Plus should be taken orally. Shake the bottle well before use. Use the provided measuring device to ensure accurate dosing. If you are unsure about the appropriate dose or have any questions, consult your healthcare professional.

Mechanism of Action

Ibuprofen, one of the active ingredients in Metagesic Plus, works by inhibiting the production of certain chemicals in the body called prostaglandins. These chemicals are involved in the process of inflammation, pain, and fever. By reducing the levels of prostaglandins, Ibuprofen helps alleviate pain and reduce fever.

Paracetamol, the other active ingredient in Metagesic Plus, works by blocking the production of certain chemicals in the brain that are responsible for pain and fever. It helps to lower the body temperature and provides relief from pain.

Side Effects

Common side effects may include nausea, upset stomach, and dizziness. These side effects are usually mild and temporary.

In rare cases, Metagesic Plus may cause more serious side effects, such as allergic reactions, stomach ulcers, or liver problems. Seek immediate medical attention if you experience any signs of an allergic reaction, such as rash, itching, swelling, dizziness, or difficulty breathing. Discontinue the medication and consult your healthcare professional if you experience any severe or persistent side effects.

Drug Interactions

Metagesic Plus may interact with certain medications, including but not limited to:

• Blood thinners (e.g., warfarin)
• Other NSAIDs (e.g., aspirin, naproxen)
• Antidepressants (e.g., selective serotonin reuptake inhibitors)
• Diuretics (e.g., furosemide)
• Lithium

These are not the only possible drug interactions. Inform your healthcare professional about all the medications you are taking, including prescription, over-the-counter, and herbal products, to avoid potential interactions.

Precautions

Before using Metagesic Plus, inform your healthcare professional about any known allergies, medical conditions, or medications you are currently taking. This medication may not be suitable for everyone, especially those with a history of certain conditions, such as stomach ulcers, liver or kidney disease, asthma, or bleeding disorders.

Metagesic Plus should be used with caution in elderly individuals, as they may be more prone to certain side effects. Follow the recommended dosage and avoid exceeding the maximum daily dose.

Avoid consuming alcohol while taking Metagesic Plus, as it may increase the risk of liver damage.

Storage

Metagesic Plus should be stored at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed when not in use. Do not freeze the medication. Keep it out of reach of children and pets.

Patient Tips

• Take Metagesic Plus with or after food to help minimize stomach upset.
• If you miss a dose, take it as soon as possible. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Do not exceed the recommended dosage or use the medication for a prolonged period without consulting your healthcare professional.
• If your symptoms worsen or persist after a few days of using Metagesic Plus, consult your healthcare professional.
• If you have any concerns or questions about the medication, speak with your healthcare professional or pharmacist for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Ibuprofen for adults: painkiller which also treats inflammation (NHS UK) [Accessed 21 Jun. 2024] (online) Available at:
• Anadin Ibuprofen 200 mg Tablets (Health Professionals SmPC) Available at:
• Ibuprofen (Drugs.com) [Accessed 14 Jun. 2024] (online) Available at:
• ibuprofen (RX/OTC) [Accessed 19 Jun. 2024] (online) Available at:
• Ibuprofen (MedlinePlus) [Accessed 7 Jun. 2024] (online) Available at:
• Ha MW, Paek SM. Recent Advances in the Synthesis of Ibuprofen and Naproxen. Molecules. 2021 Aug 7;26(16):4792. doi: 10.3390/molecules26164792. [Accessed 0 Jun. 2024] Available at: