Metrogyl-M Ointment

Introduction

Metrogyl-M is a topical medication that combines two active ingredients: Mupirocin and Metronidazole. Mupirocin is an antibiotic that helps to treat bacterial skin infections, while Metronidazole is an anti-inflammatory and anti-parasitic agent. This combination ointment provides a broad-spectrum approach to help resolve skin infections and reduce inflammation.

Uses

Metrogyl-M is primarily prescribed for the treatment of skin infections caused by bacteria. It is commonly used to treat impetigo, a highly contagious skin condition characterized by red sores that can ooze and crust. Additionally, Metrogyl-M may be used to treat other bacterial skin infections, such as folliculitis and infected eczema.

Dosage and Administration

follow your healthcare provider’s instructions when using Metrogyl-M. Typically, a thin layer of the ointment should be applied to the affected area of the skin three times a day. Before applying the ointment, clean and dry the affected area thoroughly. Gently rub in the ointment until it is evenly distributed. Wash your hands before and after applying the ointment, unless your hands are the affected area.

Mechanism of Action

Metrogyl-M works by inhibiting the growth of bacteria and reducing inflammation. Mupirocin prevents the bacteria from producing essential proteins needed for their survival, ultimately leading to their death. Metronidazole, the other active ingredient, has anti-inflammatory properties and can help reduce redness, swelling, and itching associated with bacterial skin infections.

Side Effects

Common side effects may include skin irritation, itching, and redness at the application site. These side effects are usually mild and should improve with continued use. However, if you experience any severe or persistent side effects, such as severe skin rash, blistering, or signs of an allergic reaction (e.g., difficulty breathing, swelling of the face or throat), discontinue use and seek medical attention immediately.

Drug Interactions

Before using Metrogyl-M, inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. There are no known significant drug interactions with Metrogyl-M. However, it is always best to consult with your healthcare provider to ensure there are no potential interactions that may affect the effectiveness or safety of the medication.

Precautions

Certain precautions should be considered when using Metrogyl-M. If you have a known allergy to Mupirocin, Metronidazole, or any other ingredients in the ointment, you should not use this medication. Additionally, avoid contact with the eyes, nose, mouth, or any mucous membranes. If accidental contact occurs, rinse thoroughly with water. If your symptoms do not improve within a few days or worsen, consult your healthcare provider for further evaluation.

Storage

Metrogyl-M should be stored at room temperature, away from direct sunlight and moisture. Keep the ointment in its original container, tightly closed, and out of reach of children. Do not freeze the ointment. If the medication has expired or is no longer needed, dispose of it properly according to local regulations.

Patient Tips

• Follow the prescribed dosage and application instructions provided by your healthcare provider.
• Do not use Metrogyl-M for longer than recommended, unless instructed by your healthcare provider.
• Avoid applying the ointment to open wounds, broken or damaged skin, or areas with a known viral infection.
• If you miss a dose, apply it as soon as you remember. However, if it is close to the time of your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• If you have any concerns or questions about the use of Metrogyl-M, consult your healthcare provider for guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Metronidazole: antibiotic to treat infections (NHS UK) [Accessed 6 Jun. 2024] (online) Available at:
• Acea 0.75% w/w Gel (Health Professionals SmPC) Available at:
• Metronidazole (Drugs.com) [Accessed 26 Jun. 2024] (online) Available at:
• metronidazole (RX) [Accessed 5 Jun. 2024] (online) Available at:
• Metronidazole Injection (MedlinePlus) [Accessed 5 Jun. 2024] (online) Available at:
• Dingsdag SA, Hunter N. Metronidazole: an update on metabolism, structure-cytotoxicity and resistance mechanisms. J Antimicrob Chemother. 2018 Feb 1;73(2):265-279. doi: 10.1093/jac/dkx351. [Accessed 12 Jun. 2024] Available at: