Miokool-DSR Capsule

Introduction

Miokool-DSR is a prescription medication that contains two active ingredients: Domperidone and Esomeprazole. Domperidone is a medication that belongs to the class of drugs called dopamine antagonists. Esomeprazole is a proton pump inhibitor (PPI). This combination medication is primarily used to treat conditions associated with excessive stomach acid, such as gastroesophageal reflux disease (GERD) and gastric ulcers.

Uses

Miokool-DSR is prescribed to manage symptoms related to excessive stomach acid production. It is commonly used to relieve heartburn, acid reflux, and other symptoms of GERD. Additionally, it can help heal and prevent gastric ulcers caused by stomach acid.

Dosage and Administration

follow the dosage instructions provided by your healthcare provider. Generally, the recommended dose of Miokool-DSR is one capsule taken orally, usually once daily before a meal. Swallow the capsule whole with a glass of water, without crushing or chewing it.

Mechanism of Action

Miokool-DSR contains two active ingredients that work in different ways to provide therapeutic effects. Domperidone acts by blocking dopamine receptors in the brain and gastrointestinal tract, which helps to enhance the movement of food through the stomach and intestines. Esomeprazole, on the other hand, reduces the production of stomach acid by inhibiting the proton pump in the gastric cells. By combining these two medications, Miokool-DSR helps reduce the symptoms associated with excessive stomach acid.

Side Effects

Common side effects may include headache, dizziness, dry mouth, and gastrointestinal disturbances such as stomach discomfort or diarrhea. If any of these side effects persist or worsen, consult your healthcare provider.

In rare cases, Miokool-DSR may cause serious side effects. Contact your healthcare provider immediately if you experience symptoms such as irregular heartbeat, severe abdominal pain, severe allergic reactions (rash, itching, swelling), or signs of liver problems (such as yellowing of the skin or eyes, dark urine, or persistent nausea). Seek medical attention if you experience any severe or unexpected side effects.

Drug Interactions

Miokool-DSR may interact with certain medications, including but not limited to medications metabolized by the CYP2C19 enzyme, antifungal medications (such as ketoconazole), and certain antibiotics (such as clarithromycin). These interactions can affect the effectiveness or increase the risk of side effects of Miokool-DSR. Inform your healthcare provider about all the medications you are currently taking to avoid potential interactions.

Precautions

Before using Miokool-DSR, inform your healthcare provider about any existing medical conditions, including liver problems, kidney problems, or any allergies. Additionally, let your healthcare provider know about all the medications you are taking, including prescription, over-the-counter, and herbal products.

Miokool-DSR should be used with caution in individuals with certain medical conditions. It is contraindicated in patients with known hypersensitivity to any of the components of the medication. Consult your healthcare provider to determine if Miokool-DSR is appropriate for your specific condition.

Storage

Patient Tips

• Take Miokool-DSR exactly as prescribed by your healthcare provider. Do not exceed the recommended dose or duration of treatment.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• maintain a healthy lifestyle and follow dietary recommendations while using Miokool-DSR. Avoid triggering foods and beverages that may worsen symptoms of GERD.
• If you experience any new or worsening symptoms or have concerns about the medication, do not hesitate to consult your healthcare provider for guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Domperidone: anti-sickness medicine for nausea and vomiting (NHS UK) [Accessed 10 Jun. 2024] (online) Available at:
• Domperidone 10 mg film-coated tablets (Health Professionals SmPC) Available at:
• Domperidone (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
• esomeprazole mag-glycerin kit, capsule delayed release and spray (kit, dr spray) (RX) [Accessed 27 Jun. 2024] (online) Available at:
• Definitions of Digestive Terms (International Foundation for Gastrointestinal Disorders) [Accessed 3 Jun. 2024] (online) Available at:
• Puoti MG, Assa A, Benninga M, Broekaert IJ, Carpi FJM, Deganello Saccomani M, Dolinsek J, Homan M, Mas E, Miele E, Tzivinikos C, Thomson M, Borrelli O. Drugs in Focus: Domperidone. J Pediatr Gastroenterol Nutr. 2023 Aug 1;77(2):e13-e22. doi: 10.1097/MPG.0000000000003822. Epub 2023 May 9. [Accessed 7 Jun. 2024] Available at: