MP Oral Suspension

Introduction

MP is a prescription medication that combines two active ingredients: Metformin and Teneligliptin. Metformin is a widely-used medication for the treatment of type 2 diabetes, while Teneligliptin is a newer class of medication known as a dipeptidyl peptidase-4 (DPP-4) inhibitor. MP is available under the brand name MP and is primarily used for the management of type 2 diabetes.

Uses

MP is prescribed to help control blood sugar levels in patients with type 2 diabetes. It is used in combination with diet and exercise to improve glycemic control. By reducing the amount of sugar produced by the liver, increasing the sensitivity of muscle and fat cells to insulin, and decreasing the amount of sugar absorbed from the intestines, MP helps to lower and stabilize blood glucose levels.

Dosage and Administration

The dosage of MP will depend on various factors, including the patient’s age, medical condition, and response to treatment. Follow the instructions provided by your healthcare provider. Generally, the usual starting dose for adults is one to two teaspoons (5-10 mL) once or twice daily, with or after a meal. The dosage may be adjusted based on blood sugar levels and the individual’s response to treatment. Take the medication regularly to achieve the best results.

Mechanism of Action

MP contains Metformin and Teneligliptin, which work together to improve glycemic control in patients with type 2 diabetes. Metformin primarily acts by reducing the amount of sugar produced by the liver and increasing the sensitivity of muscle and fat cells to insulin. Teneligliptin, on the other hand, works by inhibiting the action of an enzyme called DPP-4, which increases the levels of incretin hormones in the body. These hormones help to stimulate the release of insulin and suppress the release of glucagon, a hormone that raises blood sugar levels. By targeting multiple mechanisms involved in glucose regulation, MP helps to lower and maintain blood sugar levels within the target range.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, stomach discomfort, and headache. These side effects are usually mild and subside on their own as your body adjusts to the medication. However, if these side effects persist or worsen, consult your healthcare provider.

In rare cases, MP may cause more serious side effects. These may include lactic acidosis (a buildup of lactic acid in the blood), hypoglycemia (low blood sugar), and allergic reactions. Signs of lactic acidosis may include weakness, tiredness, muscle pain, difficulty breathing, and irregular heartbeat. Signs of hypoglycemia may include sweating, dizziness, shakiness, confusion, and blurred vision. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal products. MP may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. Some common drug interactions include:

• Certain medications used to treat heart conditions, such as digoxin or beta-blockers
• Diuretics (water pills)
• Certain antibiotics like ciprofloxacin or trimethoprim
• Certain antifungal medications like fluconazole
• Certain medications used to treat high blood pressure, such as ACE inhibitors or angiotensin receptor blockers

discuss all medications you are taking with your healthcare provider to avoid potential drug interactions.

Precautions

Before starting MP, inform your healthcare provider about any medical conditions you have, including kidney or liver problems, heart disease, or a history of lactic acidosis. Disclose any allergies or sensitivities to medications.

MP is contraindicated in patients with severe kidney impairment, liver disease, or a history of lactic acidosis. Follow your healthcare provider’s instructions and undergo regular monitoring of kidney function while taking this medication.

Storage

MP should be stored at room temperature, away from moisture and heat. Keep the bottle tightly closed when not in use. Do not freeze the medication. Keep all medications out of reach of children.

Patient Tips

Here are some additional tips to help you get the most out of your treatment with MP:

• Take the medication as prescribed by your healthcare provider. Do not change the dosage or stop taking the medication without consulting your healthcare provider.
• Follow a healthy diet and exercise regularly to support the effectiveness of the medication.
• Monitor your blood sugar levels regularly and keep track of any changes or patterns. This will help you and your healthcare provider make adjustments to your treatment plan if necessary.
• If you experience any unusual symptoms or side effects while taking MP, contact your healthcare provider.
• Attend regular check-ups with your healthcare provider to monitor your progress and discuss any concerns or questions you may have.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Metformin: a medicine to treat type 2 diabetes (NHS UK) [Accessed 10 Jun. 2024] (online) Available at:
• Competact 15 mg/850 mg film-coated tablets (Health Professionals SmPC) Available at:
• Metformin (Drugs.com) [Accessed 6 Jun. 2024] (online) Available at:
• metformin (RX) [Accessed 21 Jun. 2024] (online) Available at:
• Metformin (MedlinePlus) [Accessed 2 Jun. 2024] (online) Available at:
• LaMoia TE, Shulman GI. Cellular and Molecular Mechanisms of Metformin Action. Endocr Rev. 2021 Jan 28;42(1):77-96. doi: 10.1210/endrev/bnaa023. [Accessed 21 Jun. 2024] Available at: