Napain Plus Tablet

Introduction

Napain Plus is a prescription medication that combines four active ingredients: Nimesulide, Paracetamol, Magnesium Trisilicate, and Chlorpheniramine Maleate. It is available in tablet form and is commonly used to relieve pain, reduce inflammation, and provide relief from symptoms associated with allergies and the common cold.

Uses

Napain Plus is prescribed to patients for the treatment of various conditions, including:

• Mild to moderate pain, such as headaches, toothaches, and menstrual pain.
• Inflammatory conditions, such as arthritis and musculoskeletal disorders.
• Allergies, including hay fever and allergic rhinitis.
• Symptoms of the common cold, such as nasal congestion and sneezing.

Dosage and Administration

follow the dosage instructions provided by your healthcare professional. The recommended dosage for Napain Plus may vary depending on the specific condition being treated and the patient’s age, weight, and overall health. It is typically taken orally with water, preferably after meals to minimize the risk of stomach upset. Do not crush or chew the tablet; swallow it whole.

Mechanism of Action

Napain Plus contains four active ingredients that work together to provide relief from pain, inflammation, and allergy symptoms.

• Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) that helps to reduce pain and inflammation by inhibiting the production of certain chemicals in the body.
• Paracetamol is a fever reducer and pain reliever that works by blocking the production of certain chemicals in the brain.
• Magnesium Trisilicate is an antacid that helps to neutralize excess stomach acid, reducing the risk of gastrointestinal side effects.
• Chlorpheniramine Maleate is an antihistamine that helps to relieve allergy symptoms by blocking the effects of histamine in the body.

Side Effects

Common side effects may include drowsiness, dizziness, upset stomach, and dry mouth. These side effects are usually mild and temporary. However, if you experience any serious side effects such as severe allergic reactions, difficulty breathing, or persistent stomach pain, seek medical attention immediately.

Drug Interactions

Napain Plus may interact with certain medications, including but not limited to:

• Blood thinners (e.g., Warfarin): Risk of increased bleeding.
• Antidepressants, sedatives, or tranquilizers: Increased risk of drowsiness.
• Other NSAIDs: Increased risk of gastrointestinal bleeding.
• Alcohol: Increased risk of liver damage.

Inform your healthcare professional about all the medications you are currently taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions.

Precautions

Before taking Napain Plus, consider the following precautions:

• Do not take this medication if you have a known allergy to any of its active ingredients.
• Inform your healthcare professional about any existing medical conditions, such as liver or kidney disease, asthma, or stomach ulcers.
• Avoid alcohol consumption while taking this medication, as it may increase the risk of liver damage.
• Napain Plus should be used with caution in elderly patients and children, as they may be more susceptible to certain side effects.

Storage

Napain Plus should be stored in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not use the medication after the expiration date printed on the packaging.

Patient Tips

• Take the medication as prescribed by your healthcare professional. Do not exceed the recommended dosage or use it for longer than recommended.
• If you experience any bothersome side effects or have concerns about the medication, consult your healthcare professional.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not share this medication with others, even if they have similar symptoms. Each individual’s condition may require a specific treatment plan.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Chlorphenamine: drowsy (sedating) antihistamine (NHS UK) [Accessed 29 Jun. 2024] (online) Available at:
• CitraFleet, Powder for oral solution in sachet (Health Professionals SmPC) Available at:
• Chlorpheniramine (Drugs.com) [Accessed 27 Jun. 2024] (online) Available at:
• chlorpheniramine maleate (OTC) [Accessed 11 Jun. 2024] (online) Available at:
• Codeine (MedlinePlus) [Accessed 21 Jun. 2024] (online) Available at:
• Kumar M, Upadhayay P, Shankar R, Joshi M, Bhatt S, Malik A. Chlorpheniramine maleate containing chitosan-based nanoparticle-loaded thermosensitive in situ gel for management in allergic rhinitis. Drug Deliv Transl Res. 2019 Dec;9(6):1017-1026. doi: 10.1007/s13346-019-00639-w. [Accessed 13 Jun. 2024] Available at: