Natrilam 5 Tablet SR

Introduction

Natrilam is a prescription medication that contains two active ingredients: Amlodipine and Indapamide. Amlodipine is a calcium channel blocker, while Indapamide is a diuretic. This combination medication is primarily used to treat high blood pressure (hypertension) in adults.

Uses

Natrilam is prescribed to help lower blood pressure in individuals with hypertension. By reducing the amount of calcium that enters the blood vessels, Amlodipine helps to relax and widen the blood vessels, allowing for smoother blood flow. Indapamide, on the other hand, promotes diuresis, which helps to reduce excess fluid in the body. Together, these actions help to lower blood pressure and reduce the workload on the heart.

Dosage and Administration

Natrilam should be taken exactly as prescribed by your healthcare provider. The typical recommended dose is one tablet per day, preferably in the morning. The tablet should be swallowed whole with a glass of water and should not be crushed or chewed. It can be taken with or without food, but take it consistently at the same time each day to maintain a steady level of medication in the body.

Mechanism of Action

Amlodipine, one of the active ingredients in Natrilam, works by blocking the entry of calcium into the smooth muscle cells of the blood vessels. By doing so, it helps the blood vessels to relax, which in turn reduces the resistance to blood flow and lowers blood pressure. Indapamide, the other active ingredient, acts as a diuretic, promoting the excretion of excess fluid and salt from the body, further aiding in the reduction of blood pressure.

Side Effects

Common side effects may include swelling of the ankles or feet, dizziness, flushing, headache, and fatigue. These side effects are usually mild and temporary. However, if you experience any of the following serious side effects, seek medical attention immediately: severe dizziness, irregular heartbeat, chest pain, difficulty breathing, or signs of an allergic reaction (such as rash, itching, or swelling).

Drug Interactions

Natrilam may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. Inform your healthcare provider about all the medications you are currently taking, including prescription medications, over-the-counter drugs, and herbal supplements. Some common drug interactions to be aware of include interactions with other blood pressure medications, certain antibiotics, antifungal medications, and grapefruit juice. Your healthcare provider can provide specific guidance on potential drug interactions.

Precautions

Before starting Natrilam, inform your healthcare provider about any medical conditions you have, especially if you have liver or kidney problems, heart disease, or a history of allergic reactions. This medication may not be suitable for everyone, and your healthcare provider will consider these factors when determining the appropriate treatment for you. Additionally, avoid alcohol while taking Natrilam, as it may increase the risk of side effects and affect the medication’s effectiveness.

Storage

Natrilam should be stored at room temperature, away from direct sunlight and moisture. Keep the medication in its original packaging and out of reach of children. Do not use the medication if it has expired or if the packaging appears to be damaged.

Patient Tips

Here are a few tips to help you get the most out of your treatment with Natrilam:

• Take the medication at the same time every day to maintain a consistent level of medication in your body.
• If you forget to take a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Avoid sudden changes in body position, such as standing up quickly, as Amlodipine may cause dizziness or lightheadedness.
• Keep regular appointments with your healthcare provider to monitor your blood pressure and assess your response to the medication.
• If you have any concerns or questions about your medication or its side effects, do not hesitate to reach out to your healthcare provider for guidance. They are there to support you throughout your treatment journey.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

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• Amlodipine / Valsartan 10 mg / 160 mg film-coated tablets (Health Professionals SmPC) Available at:
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• Amlodipine (MedlinePlus) [Accessed 24 Jun. 2024] (online) Available at:
• van Zwieten PA. Amlodipine: an overview of its pharmacodynamic and pharmacokinetic properties. Clin Cardiol. 1994 Sep;17(9 Suppl 3):III3-6. [Accessed 6 Jun. 2024] Available at: