Introduction
Naxiflo D is a prescription medication that combines two active ingredients: Tamsulosin and Dutasteride. Tamsulosin is a selective alpha-blocker, while Dutasteride is a 5-alpha-reductase inhibitor. This combination medication is primarily used to treat symptoms associated with an enlarged prostate gland, a condition known as benign prostatic hyperplasia (BPH). It is available under the brand name Naxiflo D.
Uses
Naxiflo D is prescribed to alleviate the symptoms of benign prostatic hyperplasia (BPH). BPH is a common condition that occurs when the prostate gland, which is located below the bladder, becomes enlarged. Symptoms of BPH can include difficulty urinating, weak urine flow, frequent urination (especially at night), and the feeling of incomplete bladder emptying. Naxiflo D helps to relax the muscles in the prostate and bladder, making it easier to urinate and relieving the associated symptoms.
Dosage and Administration
The recommended dosage of Naxiflo D is one capsule taken orally once daily, preferably after a meal. Follow the instructions provided by your healthcare professional regarding the dosage and duration of treatment. Swallow the capsule whole with a glass of water; do not crush, chew, or open the capsule.
Mechanism of Action
Naxiflo D works in two ways to alleviate the symptoms of benign prostatic hyperplasia (BPH). Tamsulosin, being an alpha-blocker, relaxes the muscles in the prostate and bladder neck, which helps to improve urine flow and reduce symptoms such as difficulty urinating. Dutasteride, on the other hand, inhibits the enzyme 5-alpha-reductase, which is responsible for converting testosterone to dihydrotestosterone (DHT). By reducing DHT levels, Dutasteride helps to shrink the enlarged prostate gland over time.
Side Effects
Common side effects may include dizziness, headache, runny nose, and abnormal ejaculation. These side effects are generally mild and temporary. However, if they persist or worsen, consult your healthcare professional.
In rare cases, Naxiflo D may cause more serious side effects such as allergic reactions, including rash, itching, swelling, severe dizziness, and trouble breathing. If you experience any of these symptoms, seek immediate medical attention.
Drug Interactions
Naxiflo D may interact with certain medications, including other alpha-blockers and 5-alpha-reductase inhibitors. Inform your healthcare professional about all the medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins. They can evaluate potential drug interactions and adjust your treatment plan accordingly.
Precautions
Before taking Naxiflo D, inform your healthcare professional about any existing medical conditions, including liver disease, kidney disease, and allergies. This medication may not be suitable for individuals with certain conditions or those who are allergic to Tamsulosin, Dutasteride, or other similar medications.
Naxiflo D is not intended for use in women or children. Pregnant women or those planning to become pregnant should avoid handling crushed or broken capsules, as the active ingredients may be absorbed through the skin and harm the developing fetus.
Storage
Naxiflo D should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use the medication if the packaging is damaged or if the expiry date has passed. Proper storage helps to maintain the effectiveness and safety of the medication.
Patient Tips
- Take the medication at the same time each day to establish a routine.
- Do not skip doses or stop taking the medication without consulting your healthcare professional.
- If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- It may take several weeks to notice the full benefits of Naxiflo D. Be patient and continue taking the medication as prescribed.
- If you have any questions or concerns about your treatment, do not hesitate to reach out to your healthcare professional for guidance.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Tamsulosin: a medicine for symptoms of an enlarged prostate (NHS UK) [Accessed 15 Jun. 2024] (online) Available at:
- Avodart 0.5mg soft capsules (Health Professionals SmPC) Available at:
- Dutasteride (Drugs.com) [Accessed 21 Jun. 2024] (online) Available at:
- dutasteride (RX) [Accessed 7 Jun. 2024] (online) Available at:
- Dutasteride (MedlinePlus) [Accessed 10 Jun. 2024] (online) Available at:
- Gupta AK, Talukder M, Williams G. Comparison of oral minoxidil, finasteride, and dutasteride for treating androgenetic alopecia. J Dermatolog Treat. 2022 Nov;33(7):2946-2962. doi: 10.1080/09546634.2022.2109567. Epub 2022 Aug 15. [Accessed 25 Jun. 2024] Available at:
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