Necflo-M Suspension

Introduction

Necflo-M is a prescription medication that combines three active ingredients: Ofloxacin, Metronidazole, and Simethicone. Ofloxacin is a fluoroquinolone antibiotic, Metronidazole is an antiprotozoal and antibacterial agent, and Simethicone is an anti-gas medication. This combination medication is used to treat various gastrointestinal infections and conditions.

Uses

Necflo-M is prescribed to treat certain types of gastrointestinal infections, including diarrhea caused by bacterial or protozoal infections. It may also be used to treat certain types of stomach or intestinal ulcers. Additionally, it can help relieve symptoms such as gas and bloating.

Dosage and Administration

follow your healthcare provider’s instructions regarding the dosage and administration of Necflo-M. The dosage may vary depending on the specific condition being treated and the severity of the infection. The suspension should be taken orally and may be taken with or without food. Shake the bottle well before each use to ensure proper mixing of the medication.

Mechanism of Action

Necflo-M works by targeting and inhibiting the growth of bacteria and protozoa that may be causing the infection. Ofloxacin, as a fluoroquinolone antibiotic, works by interfering with the DNA replication process of the microorganisms, preventing them from multiplying. Metronidazole, on the other hand, disrupts the DNA structure of the microorganisms and inhibits their ability to survive and reproduce. Simethicone helps to relieve gas and bloating by breaking down gas bubbles in the digestive system.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, stomach discomfort, and a metallic taste in the mouth. If any of these side effects persist or worsen, consult your healthcare provider.

In some cases, Necflo-M may cause more serious side effects. These may include severe allergic reactions, such as rash, itching, swelling, dizziness, or difficulty breathing. If you experience any of these symptoms, seek immediate medical attention.

Drug Interactions

Necflo-M may interact with certain medications, including anticoagulants (blood thinners), certain antibiotics, and medications that affect liver enzymes. Inform your healthcare provider about all the medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins, to avoid potential drug interactions.

Precautions

Before taking Necflo-M, inform your healthcare provider about any medical conditions you have, especially if you have a history of liver disease, kidney disease, or blood disorders. This medication should be used with caution in pregnant or breastfeeding women, as well as in children, as safety and effectiveness in these populations have not been established.

Necflo-M should not be used by individuals who are allergic to any of its active ingredients or who have a history of hypersensitivity to fluoroquinolone antibiotics or metronidazole.

Storage

Necflo-M should be stored at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed when not in use. Do not freeze the medication. Keep it out of reach of children and dispose of any unused medication properly according to local regulations.

Patient Tips

• Take Necflo-M as prescribed by your healthcare provider and complete the full course of treatment, even if you start to feel better.
• If you experience severe or persistent diarrhea while taking this medication, inform your healthcare provider, as it could be a sign of a serious infection.
• Avoid consuming alcohol while taking Necflo-M, as it may increase the risk of certain side effects.
• If you are taking any other medications or supplements, consult your healthcare provider or pharmacist to ensure there are no potential interactions with Necflo-M.
• If you have any questions or concerns about your treatment with Necflo-M, do not hesitate to reach out to your healthcare provider for clarification and guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Metronidazole: antibiotic to treat infections (NHS UK) [Accessed 6 Jun. 2024] (online) Available at:
• Acea 0.75% w/w Gel (Health Professionals SmPC) Available at:
• Metronidazole (Drugs.com) [Accessed 26 Jun. 2024] (online) Available at:
• metronidazole (RX) [Accessed 5 Jun. 2024] (online) Available at:
• Metronidazole Injection (MedlinePlus) [Accessed 5 Jun. 2024] (online) Available at:
• Dingsdag SA, Hunter N. Metronidazole: an update on metabolism, structure-cytotoxicity and resistance mechanisms. J Antimicrob Chemother. 2018 Feb 1;73(2):265-279. doi: 10.1093/jac/dkx351. [Accessed 12 Jun. 2024] Available at: