Introduction
NHC is a topical medication that contains the active ingredients Chloramphenicol and Hydrocortisone. It is available under the brand name NHC. This ointment is primarily used for the treatment of certain skin infections and inflammatory conditions.
Uses
NHC is prescribed for the following conditions:
- Bacterial skin infections: It is effective against a variety of bacteria that can cause skin infections, such as impetigo and infected eczema.
- Inflammatory skin conditions: It can also help reduce inflammation in certain skin conditions, including dermatitis and allergic reactions.
Dosage and Administration
follow the instructions provided by your healthcare professional. Generally, NHC is applied thinly to the affected area of the skin three to four times a day. Before applying the ointment, clean and dry the affected area thoroughly. Avoid covering the treated area with bandages or dressings, unless specifically instructed by your healthcare provider.
Mechanism of Action
NHC contains two active ingredients, Chloramphenicol and Hydrocortisone, which work in different ways to treat skin infections and reduce inflammation:
- Chloramphenicol is an antibiotic that inhibits the growth of bacteria by interfering with their ability to produce essential proteins.
- Hydrocortisone is a corticosteroid that helps reduce inflammation and itching by suppressing the immune response in the affected area.
Side Effects
Common side effects may include:
- Itching or irritation at the application site
- Dry skin
- Burning or stinging sensation
If you experience any of the following serious side effects, seek medical attention immediately:
- Allergic reaction: This may include rash, itching, swelling, severe dizziness, or difficulty breathing.
- Signs of skin infection: If the condition worsens or you develop signs of a secondary skin infection, such as increased pain, redness, swelling, or pus.
Drug Interactions
inform your healthcare professional about all the medications you are taking, including over-the-counter drugs and herbal supplements. Some medications may interact with NHC and affect its effectiveness or increase the risk of side effects. Common drug interactions may include:
- Other topical medications: Using multiple topical medications on the same area of skin may increase the absorption of the active ingredients and the risk of side effects.
- Oral corticosteroids: Taking oral corticosteroids while using NHC may increase the risk of systemic side effects.
Precautions
Before using NHC, take the following precautions:
- Allergies: If you are allergic to Chloramphenicol, Hydrocortisone, or any other ingredients in the ointment, avoid using it.
- Pregnancy and breastfeeding: Consult your healthcare professional before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.
- Other medications: Inform your healthcare professional about all the medications you are taking to avoid potential interactions.
- Avoid contact with eyes: NHC should not be applied to the eyes or near the eye area.
Storage
To ensure the effectiveness and safety of NHC, it should be stored properly. Keep the ointment in a cool, dry place away from direct sunlight. Make sure to keep it out of reach of children and pets. Do not use the ointment if it has passed the expiration date.
Patient Tips
Here are some additional tips for patients using NHC:
- Wash your hands before and after applying the ointment.
- Avoid using the ointment on broken or damaged skin unless specifically instructed by your healthcare professional.
- If the symptoms do not improve within a few days of using the ointment, or if they worsen, consult your healthcare professional.
- Do not use more than the recommended amount of ointment, as it may increase the risk of side effects.
- If you accidentally swallow the ointment, seek medical attention immediately.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Chloramphenicol: antibiotic to treat bacterial infections (NHS UK) [Accessed 26 Jun. 2024] (online) Available at:
- Boots Infected Eyes 1%w/w Eye Ointment (Health Professionals SmPC) Available at:
- Chloramphenicol (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
- chloramphenicol (ophth) solution (RX) [Accessed 13 Jun. 2024] (online) Available at:
- Chloramphenicol Injection (MedlinePlus) [Accessed 24 Jun. 2024] (online) Available at:
- Ingall D, Sherman JD. Chloramphenicol. Pediatr Clin North Am. 1968 Feb;15(1):57-72. doi: 10.1016/s0031-3955(16)32088-0. [Accessed 18 Jun. 2024] Available at:
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