Nikoran IV 48 Injection

Introduction

Nikoran IV is a medication that contains the active ingredient Nicorandil. It is available in the form of an injection and is used for the treatment of certain heart conditions.

Uses

Nikoran IV is primarily prescribed for the following conditions:

• Angina pectoris: It is used to relieve chest pain or discomfort caused by reduced blood flow to the heart muscle.
• Coronary artery spasm: It is used to prevent and treat spasms in the blood vessels of the heart.

Dosage and Administration

The dosage and administration of Nikoran IV should be determined by a healthcare professional, such as a doctor or nurse. It is typically administered as an intravenous injection. The specific dosage and frequency of administration will depend on the individual patient’s condition and response to treatment.

Mechanism of Action

Nikoran IV works by relaxing and widening the blood vessels, which helps to improve blood flow to the heart. It also has a direct effect on the heart muscle, helping to reduce the workload on the heart and relieve symptoms of angina.

Side Effects

Common side effects may include headache, dizziness, flushing, and nausea. Note that not all patients will experience these side effects, and some may experience different or more severe side effects. If any side effects occur or persist, consult a healthcare professional.

Serious side effects are rare but may include severe allergic reactions, chest pain, irregular heartbeat, and low blood pressure. If any of these serious side effects occur, immediate medical attention should be sought.

Drug Interactions

Nikoran IV may interact with other medications, including:

• Nitroglycerin: Concurrent use with nitroglycerin or other nitrates may increase the risk of low blood pressure.
• Phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil): Concurrent use may increase the risk of low blood pressure.

Inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements, to avoid potential drug interactions.

Precautions

Before using Nikoran IV, consider the following precautions:

• Allergies: Inform your healthcare provider if you have any known allergies to Nicorandil or any other medications.
• Medical history: Inform your healthcare provider about your medical history, especially if you have a history of low blood pressure, heart problems, or kidney problems.
• Pregnancy and breastfeeding: Nikoran IV should be used with caution during pregnancy and breastfeeding. Discuss the potential risks and benefits with your healthcare provider.

Storage

Nikoran IV should be stored according to the instructions provided by the manufacturer. It is typically stored at room temperature, away from direct sunlight and moisture. Keep it out of the reach of children.

Patient Tips

Here are some additional tips for patients using Nikoran IV:

• Follow the dosage instructions provided by your healthcare provider.
• If you miss a dose, contact your healthcare provider for further instructions.
• Report any unusual or persistent side effects to your healthcare provider.
• Do not stop or change the dosage of Nikoran IV without consulting your healthcare provider.
• Keep all follow-up appointments with your healthcare provider to monitor your response to the medication.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Nicorandil: a medicine to treat chest pain (angina) (NHS UK) [Accessed 15 Jun. 2024] (online) Available at:
• Nicorandil 10mg Tablets (Health Professionals SmPC) Available at:
• Nicorandil (International database) (Drugs.com) [Accessed 26 Jun. 2024] (online) Available at:
• Egred M. Nicorandil-associated ulcerations. Eur J Gastroenterol Hepatol. 2007 May;19(5):395-8. doi: 10.1097/MEG.0b013e328010b184. [Accessed 5 Jun. 2024] Available at: