Nital 100mg/5ml Suspension

Introduction

Nital is a prescription medication that contains the active ingredient Nitazoxanide. It is available in a liquid suspension form and is commonly prescribed by healthcare professionals.

Uses

Nital is primarily used to treat certain gastrointestinal infections caused by parasites and certain types of bacteria. It is commonly prescribed for conditions such as diarrhea caused by Cryptosporidium parvum or Giardia lamblia.

Dosage and Administration

The dosage of Nital will vary depending on the age, weight, and specific condition of the patient. Follow the instructions provided by your healthcare professional. Generally, the recommended dosage for adults and children is as follows:

• Adults and children above 12 years: One 500 mg (5 mL) dose taken orally every 12 hours for 3 days.

For children aged 4 to 11 years, the dosage will depend on their weight, and it is typically calculated as 7.5 mg per kilogram of body weight. This dose is usually divided into two equal doses and taken orally every 12 hours for 3 days.

Always use the provided measuring device to ensure accurate dosage. Shake the suspension well before each use.

Mechanism of Action

Nitazoxanide, the active ingredient in Nital, works by interfering with the energy production and replication processes of certain parasites and bacteria. This helps to control the infection and reduce symptoms.

Side Effects

Common side effects may include nausea, abdominal pain, headache, and dizziness. These side effects are usually mild and temporary.

In rare cases, more serious side effects may occur. If you experience any of the following symptoms, contact your healthcare professional immediately:

• Severe allergic reactions such as rash, itching, swelling, or difficulty breathing
• Persistent or severe diarrhea
• Yellowing of the skin or eyes
• Dark urine
• Unusual bleeding or bruising
• Signs of liver problems such as abdominal pain, loss of appetite, or fatigue

Drug Interactions

inform your healthcare professional about all the medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins. Some medications may interact with Nital, potentially affecting its effectiveness or increasing the risk of side effects. Common drug interactions may include:

• Antacids containing aluminum and magnesium hydroxide: These may decrease the absorption of Nitazoxanide. If you are taking antacids, it is recommended to separate the doses by at least 2 hours.
• Rifampin: This medication may decrease the effectiveness of Nital.
• Warfarin: Nitazoxanide may increase the risk of bleeding when taken with warfarin. Close monitoring of blood clotting parameters is advised.

This is not an exhaustive list, and other medications may also interact with Nital. Always consult your healthcare professional for personalized advice.

Precautions

Before taking Nital, inform your healthcare professional if you have any allergies, medical conditions, or if you are pregnant or breastfeeding. Follow these precautions:

• Contraindications: Nital should not be used in patients with a known hypersensitivity to Nitazoxanide or any of the other ingredients in the suspension.
• Pregnancy and breastfeeding: The safety of Nital during pregnancy and breastfeeding has not been established. Consult your healthcare professional for guidance.
• Liver or kidney problems: Use caution when taking Nital if you have pre-existing liver or kidney problems. Close monitoring may be necessary.
• Children: The safety and effectiveness of Nital in children under 4 years of age have not been established.

Storage

Nital should be stored at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed when not in use. Do not freeze the medication. Always check the expiration date and discard any expired medication properly.

Patient Tips

• Take the medication as prescribed by your healthcare professional, and complete the full course of treatment.
• If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• If you have any questions or concerns about the medication, do not hesitate to contact your healthcare professional.
• Maintain good hygiene practices, such as washing hands thoroughly and avoiding contact with potentially contaminated surfaces.
• Stay hydrated by drinking plenty of fluids while taking Nital.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Nitazoxanide (Drugs.com) [Accessed 20 Jun. 2024] (online) Available at:
• nitazoxanide 500 mg tablet antiprotozoal agents (RX) [Accessed 10 Jun. 2024] (online) Available at:
• Nitazoxanide (MedlinePlus) [Accessed 29 Jun. 2024] (online) Available at:
• Al-Kuraishy HM, Al-Gareeb AI, Elekhnawy E, Batiha GE. Nitazoxanide and COVID-19: A review. Mol Biol Rep. 2022 Nov;49(11):11169-11176. doi: 10.1007/s11033-022-07822-2. Epub 2022 Sep 12. [Accessed 0 Jun. 2024] Available at: