Nitrobest Tablet SR

Introduction

Nitrobest SR is a prescription medication that contains the active ingredient Nitrofurantoin. It is available in tablet form and is used to treat certain bacterial infections in the urinary tract.

Uses

Nitrobest SR is primarily prescribed to treat urinary tract infections caused by susceptible bacteria. It is commonly used for infections of the bladder and urinary tract, including cystitis. This medication works by stopping the growth of bacteria, thereby helping to alleviate the symptoms associated with these infections.

Dosage and Administration

The dosage of Nitrobest SR will vary depending on the severity of the infection and the individual patient’s response to treatment. Follow the instructions provided by your healthcare professional. Generally, the recommended dose for adults is one tablet taken twice daily with food or milk. The tablets should be swallowed whole and not crushed or chewed. Complete the full course of treatment, even if you start feeling better before the medication is finished.

Mechanism of Action

Nitrofurantoin, the active ingredient in Nitrobest SR, works by interfering with the bacteria’s ability to produce proteins essential for their growth and survival. This prevents the bacteria from multiplying and ultimately leads to their elimination by the body’s immune system. By inhibiting bacterial growth, Nitrofurantoin helps to resolve the infection and relieve associated symptoms.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, loss of appetite, and headache. These side effects are generally mild and subside on their own. However, if they persist or worsen, consult your healthcare professional.

In rare cases, Nitrobest SR can cause more serious side effects. These may include severe allergic reactions, such as rash, swelling, or difficulty breathing. Seek immediate medical attention if you experience any of these symptoms. Additionally, if you notice any signs of liver problems, such as yellowing of the skin or eyes, dark urine, or persistent fatigue, you should contact your healthcare professional.

Drug Interactions

Nitrobest SR may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. Inform your healthcare professional about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. Some medications that may interact with Nitrobest SR include antacids containing magnesium trisilicate, certain medications used to treat gout (such as probenecid), and certain antibiotics (such as tetracyclines). Your healthcare professional will be able to advise you on any potential interactions and adjust your treatment plan accordingly.

Precautions

Before starting treatment with Nitrobest SR, inform your healthcare professional about any allergies you may have, especially to Nitrofurantoin or any other medications. Additionally, let your healthcare professional know about any medical conditions you have, especially kidney or liver problems, glucose-6-phosphate dehydrogenase (G6PD) deficiency, or a history of lung problems.

Nitrobest SR is generally not recommended during pregnancy, especially during the last month of pregnancy, as it may harm the unborn baby. It is also not recommended for use in infants younger than one month of age.

Storage

Patient Tips

• Take Nitrobest SR with food or milk to help reduce the risk of stomach upset.
• complete the full course of treatment, even if you start feeling better before the medication is finished.
• Drink plenty of fluids while taking Nitrobest SR to help flush out the bacteria from your urinary tract.
• If you experience any severe or persistent side effects, contact your healthcare professional for further guidance.
• Inform your healthcare professional about all the medications you are taking, including over-the-counter and herbal products, to prevent any potential drug interactions.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Nitrofurantoin: antibiotic to treat bacterial infections (NHS UK) [Accessed 15 Jun. 2024] (online) Available at:
• MacroBID100mg Prolonged-release Capsules (Health Professionals SmPC) Available at:
• Nitrofurantoin (Drugs.com) [Accessed 15 Jun. 2024] (online) Available at:
• nitrofurantoin (RX) [Accessed 2 Jun. 2024] (online) Available at:
• Nitrofurantoin (MedlinePlus) [Accessed 2 Jun. 2024] (online) Available at:
• Mahdizade Ari M, Dashtbin S, Ghasemi F, Shahroodian S, Kiani P, Bafandeh E, Darbandi T, Ghanavati R, Darbandi A. Nitrofurantoin: properties and potential in treatment of urinary tract infection: a narrative review. Front Cell Infect Microbiol. 2023 Jul 27;13:1148603. doi: 10.3389/fcimb.2023.1148603. eCollection 2023. [Accessed 30 Jun. 2024] Available at: