Nobeglar UNO 100IU/ml Pre-filled Pen

Introduction

The Nobeglar UNO is a prescription medication that contains the active ingredient Insulin Glargine. It is a long-acting insulin that helps control blood sugar levels in individuals with diabetes. Insulin Glargine is also known by its brand name, Nobeglar UNO.

Uses

Nobeglar UNO is primarily prescribed to individuals with type 1 diabetes and type 2 diabetes. It is used to help regulate blood sugar levels and improve glycemic control. This medication is typically used in combination with a proper diet, exercise, and other diabetes medications.

Dosage and Administration

Nobeglar UNO is intended for subcutaneous injection, which means it is injected just below the skin. The dosage and administration instructions may vary depending on individual factors such as age, weight, and blood sugar levels. Follow your healthcare provider’s instructions and the instructions provided with the pen.

Generally, the dosage is based on your individual needs and may require adjustments over time. The pen is designed for multiple doses and allows for easy dose adjustments. Never share your pen with others and to always use a new, sterile needle for each injection.

Mechanism of Action

Insulin Glargine, the active ingredient in Nobeglar UNO, works by replacing the insulin that is normally produced by the pancreas. It acts as a long-acting insulin analog, providing a steady release of insulin throughout the day. This helps to regulate blood sugar levels and maintain glycemic control.

Side Effects

Common side effects may include injection site reactions such as redness, swelling, or itching. These side effects are usually mild and tend to resolve on their own.

However, there are also some serious side effects that may occur. These can include hypoglycemia (low blood sugar), allergic reactions, and injection site infections. Be aware of the symptoms of these serious side effects and seek medical attention if they occur.

If you experience any side effects, contact your healthcare provider for guidance. They can provide further information and advice on managing any side effects that may arise.

Drug Interactions

Nobeglar UNO may interact with other medications, including over-the-counter drugs and supplements. Inform your healthcare provider about all the medications you are currently taking, including any herbal supplements or vitamins.

Some medications may increase the risk of hypoglycemia (low blood sugar) when used in combination with Nobeglar UNO. Others may interfere with the effectiveness of insulin Glargine. Your healthcare provider will be able to provide guidance on any potential drug interactions and adjust your medication regimen accordingly.

Precautions

Before using Nobeglar UNO, inform your healthcare provider about any medical conditions you have, including kidney or liver problems. This medication may not be suitable for everyone, and your healthcare provider will be able to determine if it is appropriate for you.

Be aware of any contraindications or precautions associated with Nobeglar UNO. For example, this medication should not be used during episodes of hypoglycemia (low blood sugar) or in individuals with known hypersensitivity to insulin Glargine or any of its ingredients.

Additionally, Nobeglar UNO may interact with certain medications, as mentioned earlier. Follow your healthcare provider’s instructions and discuss any concerns or questions you may have.

Storage

Nobeglar UNOs should be stored in a refrigerator at a temperature between 2°C and 8°C (36°F and 46°F). Do not freeze the pen. If necessary, the pen can be kept at room temperature (below 30°C or 86°F) for up to 28 days. After first use, the pen should be discarded after 28 days, even if it still contains insulin.

Always check the expiration date on the pen and do not use it if it has expired. Keep the pen away from direct heat or sunlight. If you have any questions about storage, consult the instructions provided with the pen or contact your healthcare provider.

Patient Tips

Here are a few tips for patients using Nobeglar UNO:

• Always check the label and expiration date before using the pen.
• Keep track of your blood sugar levels and report any significant changes to your healthcare provider.
• Follow your healthcare provider’s instructions on diet, exercise, and other diabetes management strategies.
• Carry a source of fast-acting sugar, such as glucose tablets, in case of hypoglycemia (low blood sugar).
• If you have any questions or concerns about your medication or its administration, don’t hesitate to reach out to your healthcare provider.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Type 1 diabetes – Managing insulin (NHS UK) [Accessed 6 Jun. 2024] (online) Available at:
• ABASAGLAR 100 units/mL KwikPen solution for injection in a pre-filled pen (Health Professionals SmPC) Available at:
• Insulin Glargine (Drugs.com) [Accessed 25 Jun. 2024] (online) Available at:
• insulin glargine (u-100) 100 unit/ml subcutaneous solution intermediate-, long-acting, and combination insulins (RX) [Accessed 17 Jun. 2024] (online) Available at:
• Insulin Glargine (rDNA origin) Injection [Accessed 18 Jun. 2024] (online) Available at:
• Rosenstock J, Bain SC, Gowda A, Jódar E, Liang B, Lingvay I, Nishida T, Trevisan R, Mosenzon O; ONWARDS 1 Trial Investigators. Weekly Icodec versus Daily Glargine U100 in Type 2 Diabetes without Previous Insulin. N Engl J Med. 2023 Jul 27;389(4):297-308. doi: 10.1056/NEJMoa2303208. Epub 2023 Jun 24. [Accessed 13 Jun. 2024] Available at: