Novomix 50 100IU/ml Penfill

Introduction

Novomix is a medication that contains two active ingredients: Insulin Aspart and Insulin Aspart Protamine. It is commonly known as a fast-acting insulin analog.

Uses

Novomix is primarily prescribed for patients with diabetes mellitus. It is used to help control blood sugar levels in individuals with type 1 diabetes (lack of insulin production) and type 2 diabetes (insufficient insulin production or resistance to insulin).

Dosage and Administration

The dosage of Novomix will vary depending on individual patient needs and should be determined by a healthcare professional. It is typically administered subcutaneously (under the skin) using a syringe or insulin pen. The injection site should be rotated to prevent lipodystrophy (thickened or pitted skin) from developing.

Mechanism of Action

Insulin Aspart, one of the active ingredients in Novomix, works by replacing the insulin that the body normally produces. It helps to regulate blood sugar levels by facilitating the uptake of glucose into cells for energy production. Insulin Aspart Protamine, the other active ingredient, helps to prolong the duration of action of Insulin Aspart.

Side Effects

Common side effects may include injection site reactions such as redness, swelling, or itching. These side effects are usually mild and temporary.

However, be aware of more serious side effects that may occur, such as hypoglycemia (low blood sugar) or allergic reactions. Symptoms of hypoglycemia include dizziness, confusion, sweating, and shakiness. If any serious side effects occur, seek immediate medical attention.

Drug Interactions

Novomix may interact with other medications, including oral antidiabetic drugs, non-selective beta-blockers, and certain medications that increase insulin sensitivity. Inform your healthcare provider about all the medications you are currently taking to avoid any potential drug interactions.

Precautions

Before using Novomix, inform your healthcare provider about any allergies or medical conditions you have, especially if you have liver or kidney problems. This medication may not be suitable for everyone, and your healthcare provider will assess whether it is safe and appropriate for you.

Additionally, monitor your blood sugar levels regularly and follow your healthcare provider’s instructions for insulin dosage adjustments. Use caution when driving or operating machinery, as low blood sugar levels can affect your ability to concentrate and react.

Storage

Patient Tips

• Always carry a source of fast-acting sugar, such as glucose tablets or juice, in case of hypoglycemia.
• Follow a healthy diet and exercise regularly to complement the effects of Novomix.
• Keep track of your blood sugar levels and report any significant changes to your healthcare provider.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Type 1 diabetes – Managing insulin (NHS UK) [Accessed 14 Jun. 2024] (online) Available at:
• Fiasp 100 units/mL FlexTouch solution for injection in pre-filled pen (Health Professionals SmPC) Available at:
• Insulin aspart protamine Interactions (Drugs.com) [Accessed 16 Jun. 2024] (online) Available at:
• insulin aspar prt-insulin aspart 100 unit/ml (70-30) subcutaneous soln intermediate-, long-acting, and combination insulins (RX) [Accessed 13 Jun. 2024] (online) Available at:
• Insulin (Food and Drug Administration) [Accessed 26 Jun. 2024] (online) Available at:
• Rosenstock J, Emral R, Sauque-Reyna L, Mohan V, Trescolí C, Al Sifri S, Lalic N, Alvarez A, Picard P, Bonnemaire M, Demil N, McCrimmon RJ; SoliMix Trial Investigators. Advancing Therapy in Suboptimally Controlled Basal Insulin-Treated Type 2 Diabetes: Clinical Outcomes With iGlarLixi Versus Premix BIAsp 30 in the SoliMix Randomized Controlled Trial. Diabetes Care. 2021 Jun 28;44(10):2361-70. doi: 10.2337/dc21-0393. Online ahead of print. [Accessed 30 Jun. 2024] Available at: