Obra Eye Ointment

Introduction

Obra is a prescription medication that contains the active ingredient Tobramycin. It is available under the brand name Obra. This medication is primarily used for the treatment of bacterial infections in the eyes, particularly those caused by susceptible strains of bacteria.

Uses

Obra is prescribed for the treatment of eye infections, including conjunctivitis (pink eye), blepharitis (eyelid inflammation), and other bacterial infections of the eye. It is specifically designed to target and eliminate bacteria that may be causing the infection.

Dosage and Administration

To use Obra, wash your hands thoroughly before and after application. Gently pull down the lower eyelid to create a small pocket and apply a thin strip (around 1/2 inch) of the ointment into the pocket. Avoid touching the tip of the tube to prevent contamination.

The usual dosage for adults and children is to apply the ointment to the affected eye(s) every 4 to 6 hours, or as directed by your healthcare provider. Follow the specific instructions provided by your doctor or pharmacist regarding the duration of treatment.

Mechanism of Action

Tobramycin, the active ingredient in Obra, belongs to a class of antibiotics called aminoglycosides. It works by inhibiting the growth and multiplication of bacteria that cause infections. Tobramycin binds to specific bacterial proteins, disrupting their ability to produce essential proteins for survival. This ultimately leads to the death of the bacteria, helping to clear the infection.

Side Effects

Common side effects include temporary eye irritation, burning, stinging, or itching at the site of application. These side effects are usually mild and tend to improve as your body adjusts to the medication. If these side effects persist or worsen, contact your healthcare provider.

In rare cases, some individuals may experience more serious side effects such as severe eye pain, vision changes, or signs of an allergic reaction (e.g., rash, itching, swelling). If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

inform your healthcare provider about all medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins. Obra may interact with certain medications, such as other eye medications or systemic aminoglycoside antibiotics. These interactions can affect the effectiveness or safety of the medication. Always consult with your healthcare provider or pharmacist for specific drug interaction information.

Precautions

Before using Obra, inform your healthcare provider if you have any allergies, especially to aminoglycoside antibiotics. Disclose any pre-existing medical conditions, such as kidney problems or hearing problems, as this medication may not be suitable for individuals with certain conditions.

Avoid wearing contact lenses while using Obra, as it may contain ingredients that can interact with the lenses. If you experience any new or worsening symptoms during treatment, such as eye pain, redness, or swelling, contact your healthcare provider.

Storage

Store Obra at room temperature, away from direct sunlight and moisture. Keep the tube tightly closed when not in use. Do not freeze the medication. Follow any additional storage instructions provided by your pharmacist.

Patient Tips

Here are a few tips to help you get the most out of your treatment with Obra:

• Wash your hands thoroughly before and after applying the ointment to prevent the spread of infection.
• Use a clean tissue to gently wipe away any excess ointment that may have spread beyond the eye area.
• If you are using other eye medications, wait at least 5 minutes between applying each medication to allow them to be absorbed properly.
• If you wear contact lenses, remove them before applying the ointment and wait at least 15 minutes before reinserting them.
• If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Bramitob 300 mg/4ml Nebuliser Solution (Health Professionals SmPC) Available at:
• Tobramycin injection (Drugs.com) [Accessed 2 Jun. 2024] (online) Available at:
• tobramycin 300 mg/4 ml solution for nebulization inhaled aminoglycosides (RX) [Accessed 7 Jun. 2024] (online) Available at:
• Tobramycin Injection (MedlinePlus) [Accessed 2 Jun. 2024] (online) Available at:
• Rosalia M, Chiesa E, Tottoli EM, Dorati R, Genta I, Conti B, Pisani S. Tobramycin Nanoantibiotics and Their Advantages: A Minireview. Int J Mol Sci. 2022 Nov 15;23(22):14080. doi: 10.3390/ijms232214080. [Accessed 1 Jun. 2024] Available at: