Owiglit-PG2 Tablet

Introduction

Owiglit-PG2 is a prescription medication that combines three active ingredients: Glimepiride, Metformin, and Pioglitazone. Glimepiride is a sulfonylurea antidiabetic agent, Metformin is a biguanide antidiabetic agent, and Pioglitazone is a thiazolidinedione antidiabetic agent. This combination medication is primarily used to control blood sugar levels in patients with type 2 diabetes.

Uses

Owiglit-PG2 is prescribed to patients with type 2 diabetes to help lower their blood sugar levels. It is used in conjunction with a healthy diet and regular exercise to manage diabetes effectively. This medication helps to improve the body’s response to insulin, increase insulin production, and decrease the amount of sugar produced by the liver.

Dosage and Administration

The dosage of Owiglit-PG2 will vary depending on the individual patient’s condition and response to treatment. Follow the instructions provided by your healthcare professional. Typically, the initial recommended dose for adults is one tablet taken once daily with a meal. Your healthcare provider may adjust the dose as needed to achieve optimal blood sugar control.

Mechanism of Action

Owiglit-PG2 works through the combined action of its three active ingredients. Glimepiride stimulates the release of insulin from the pancreas, helping to lower blood sugar levels. Metformin improves the body’s sensitivity to insulin and reduces the amount of glucose produced by the liver. Pioglitazone helps the body use insulin more effectively and decreases insulin resistance.

Side Effects

Common side effects may include nausea, diarrhea, stomach upset, headache, and dizziness. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, such as shortness of breath, swelling, or signs of an allergic reaction, seek medical attention immediately.

Drug Interactions

Owiglit-PG2 may interact with other medications, including certain oral contraceptives, diuretics, and blood thinners. Inform your healthcare provider about all the medications you are currently taking, including over-the-counter drugs and herbal supplements. They can determine if any potential interactions may occur and adjust your treatment plan accordingly.

Precautions

Before taking Owiglit-PG2, discuss your medical history and any pre-existing conditions with your healthcare provider. This medication may not be suitable for everyone, particularly those with a history of heart problems, liver disease, kidney disease, or bladder cancer. Avoid alcohol consumption while taking this medication, as it may increase the risk of certain side effects.

Storage

Owiglit-PG2 should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of the reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

Here are some additional tips for patients using Owiglit-PG2:

• Take the medication exactly as prescribed by your healthcare provider.
• Follow a healthy diet and exercise regularly to help manage your blood sugar levels.
• Monitor your blood sugar levels regularly and report any significant changes to your healthcare provider.
• Attend regular check-ups with your healthcare provider to monitor your progress and discuss any concerns.
• Carry a form of identification or wear a medical alert bracelet to alert others that you are taking diabetes medication.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Glimepiride: medicine to treat type 2 diabetes (NHS UK) [Accessed 4 Jun. 2024] (online) Available at:
• Glimepiride 1 mg tablets (Health Professionals SmPC) Available at:
• Glimepiride (Drugs.com) [Accessed 6 Jun. 2024] (online) Available at:
• glimepiride (amaryl) (RX) [Accessed 9 Jun. 2024] (online) Available at:
• Glimepiride (MedlinePlus) [Accessed 25 Jun. 2024] (online) Available at:
• Ridderstråle M, Andersen KR, Zeller C, Kim G, Woerle HJ, Broedl UC; EMPA-REG H2H-SU trial investigators. Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: a 104-week randomised, active-controlled, double-blind, phase 3 trial. Lancet Diabetes Endocrinol. 2014 Sep;2(9):691-700. doi: 10.1016/S2213-8587(14)70120-2. Epub 2014 Jun 16. [Accessed 3 Jun. 2024] Available at: