Oxoford MZ Syrup

Introduction

Oxoford MZ is a prescription medication that combines the active ingredients Ofloxacin, Metronidazole, and Simethicone. Ofloxacin is a fluoroquinolone antibiotic, Metronidazole is an antiprotozoal and antibacterial agent, and Simethicone is an anti-gas medication. This combination provides a comprehensive approach to treating certain infections and relieving symptoms associated with excessive gas in the gastrointestinal tract.

Uses

Oxoford MZ is used to treat a range of bacterial and protozoal infections, including respiratory tract infections, urinary tract infections, gastrointestinal infections, and skin and soft tissue infections. It is also effective in managing symptoms such as abdominal discomfort, bloating, and flatulence caused by excess gas in the digestive system.

Dosage and Administration

The recommended dosage of Oxoford MZ may vary depending on the specific condition being treated and the patient’s age and weight. Follow the instructions provided by your healthcare professional or the directions on the product label. Generally, the syrup should be taken orally, preferably with food, to minimize the risk of stomach upset. Shake the bottle well before each use and use the provided measuring device to ensure accurate dosing. Do not exceed the prescribed dosage or use the medication for a longer duration than recommended by your healthcare professional.

Mechanism of Action

Ofloxacin, one of the active ingredients in Oxoford MZ, works by inhibiting the bacterial DNA gyrase enzyme, which is essential for the replication and repair of bacterial DNA. This action prevents the growth and spread of bacteria, leading to their eventual elimination from the body. Metronidazole, on the other hand, disrupts the DNA and nucleic acid synthesis of certain protozoa and bacteria, further enhancing the antimicrobial effects. Simethicone helps reduce the surface tension of gas bubbles in the gastrointestinal tract, facilitating their expulsion and providing relief from bloating and discomfort.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, abdominal pain, headache, and dizziness. These side effects are usually mild and temporary. However, if they persist or worsen, consult your healthcare professional. In rare cases, more serious side effects may occur, such as allergic reactions, severe skin reactions, or neurological symptoms. If you experience any unusual or severe side effects, seek immediate medical attention.

Drug Interactions

Oxoford MZ may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. Inform your healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some medications that may interact with Oxoford MZ include certain anticoagulants, antacids, and drugs that affect liver enzymes. Your healthcare professional will be able to provide specific guidance on potential drug interactions and adjust your treatment plan accordingly.

Precautions

Before taking Oxoford MZ, inform your healthcare professional about any known allergies or sensitivities to any of the active ingredients or other medications. Additionally, disclose your complete medical history, including any liver or kidney problems, neurological disorders, or blood disorders. Oxoford MZ should be used with caution during pregnancy and breastfeeding, as the effects on the developing fetus or nursing infant are not fully understood. Follow your healthcare professional’s advice regarding the use of this medication in these situations.

Storage

Oxoford MZ should be stored at room temperature, away from excessive heat and moisture. Keep the bottle tightly closed when not in use to protect the medication from light and moisture. Do not use the syrup if it has expired or if you notice any signs of deterioration, such as changes in color or consistency. Keep this medication out of reach of children and pets.

Patient Tips

• Take Oxoford MZ exactly as prescribed by your healthcare professional. Do not skip doses or stop the medication prematurely, even if you start feeling better, as this may lead to incomplete treatment and potential recurrence of the infection.
• If you experience any digestive symptoms such as nausea, vomiting, or diarrhea while taking Oxoford MZ, try taking it with food to minimize stomach upset.
• complete the full course of treatment, even if you start feeling better before the prescribed duration. This helps ensure the complete eradication of the infection and reduces the risk of antibiotic resistance.
• If you are taking any other medications, check with your healthcare professional or pharmacist to ensure there are no known interactions with Oxoford MZ.
• If you have any concerns or questions about your treatment with Oxoford MZ, do not hesitate to consult your healthcare professional for guidance and clarification.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Metronidazole: antibiotic to treat infections (NHS UK) [Accessed 6 Jun. 2024] (online) Available at:
• Acea 0.75% w/w Gel (Health Professionals SmPC) Available at:
• Metronidazole (Drugs.com) [Accessed 26 Jun. 2024] (online) Available at:
• metronidazole (RX) [Accessed 5 Jun. 2024] (online) Available at:
• Metronidazole Injection (MedlinePlus) [Accessed 5 Jun. 2024] (online) Available at:
• Dingsdag SA, Hunter N. Metronidazole: an update on metabolism, structure-cytotoxicity and resistance mechanisms. J Antimicrob Chemother. 2018 Feb 1;73(2):265-279. doi: 10.1093/jac/dkx351. [Accessed 12 Jun. 2024] Available at: