Oxramet G 10mg/1mg/500mg Tablet XR

Introduction

Oxramet G is a prescription medication that contains three active ingredients: Dapagliflozin, Glimepiride, and Metformin. It is commonly used to manage blood sugar levels in adults with type 2 diabetes mellitus.

Uses

Oxramet G is prescribed to help control blood sugar in adults with type 2 diabetes mellitus. It is used as part of a comprehensive treatment plan that may include diet, exercise, and other medications. This medication helps lower blood sugar levels by increasing the excretion of glucose through the kidneys, reducing the liver’s production of glucose, and improving the body’s sensitivity to insulin.

Dosage and Administration

Oxramet G should be taken exactly as prescribed by your healthcare provider. The dosage may vary depending on your individual needs and medical condition. Follow your doctor’s instructions regarding the dose and timing of this medication.

The tablets should be swallowed whole with a glass of water. Do not crush, chew, or break the tablets unless directed by your healthcare provider. Oxramet G is typically taken once daily, with or without food. Take it at the same time each day to maintain consistent blood sugar control.

Mechanism of Action

Oxramet G works by combining three different medications with complementary mechanisms of action. Dapagliflozin is a sodium-glucose cotransporter-2 (SGLT2) inhibitor that reduces the reabsorption of glucose by the kidneys, leading to increased glucose excretion in the urine. Glimepiride is a sulfonylurea that stimulates the pancreas to produce more insulin and helps the body use insulin more effectively. Metformin is a biguanide that reduces the liver’s production of glucose and improves the body’s response to insulin.

By combining these three active ingredients, Oxramet G helps lower blood sugar levels and improves glycemic control in adults with type 2 diabetes mellitus.

Side Effects

be aware of potential side effects and to seek medical attention if they occur.

Common side effects of Oxramet G may include:

• Urinary tract infections: Symptoms may include pain or burning during urination, frequent urination, or cloudy urine.
• Hypoglycemia: Low blood sugar levels may cause symptoms such as dizziness, shakiness, sweating, confusion, or blurred vision.
• Nausea: Some individuals may experience mild to moderate nausea when starting Oxramet G. This symptom usually improves over time.

Serious side effects of Oxramet G are rare but may include:

• Ketoacidosis: This is a serious condition that may occur in individuals with type 1 or type 2 diabetes. Symptoms may include excessive thirst, frequent urination, nausea, vomiting, abdominal pain, shortness of breath, and confusion. Seek immediate medical attention if you experience these symptoms.
• Allergic reactions: Symptoms may include rash, itching, swelling, severe dizziness, or difficulty breathing. Seek immediate medical attention if you experience these symptoms.

If you experience any side effects while taking Oxramet G, contact your healthcare provider for further evaluation and guidance.

Drug Interactions

Oxramet G may interact with other medications, including prescription and over-the-counter drugs. Inform your healthcare provider about all the medications you are taking to avoid potential interactions.

Some common drug interactions with Oxramet G include:

• Certain diuretics: Combining Oxramet G with certain diuretics may increase the risk of dehydration and low blood pressure.
• Insulin and other oral antidiabetic medications: The combination of Oxramet G with insulin or other oral antidiabetic medications may increase the risk of hypoglycemia.

These are not the only possible drug interactions. Always consult your healthcare provider or pharmacist for a complete list of medications that may interact with Oxramet G.

Precautions

Before starting Oxramet G, discuss your medical history and any pre-existing conditions with your healthcare provider. Certain precautions should be considered:

• Allergy: If you are allergic to Dapagliflozin, Glimepiride, Metformin, or any other ingredients in Oxramet G, inform your healthcare provider.
• Kidney or liver problems: Oxramet G may not be suitable for individuals with severe kidney or liver impairment. Your healthcare provider will determine if this medication is appropriate for you.
• Heart problems: Inform your healthcare provider if you have a history of heart problems or if you are taking medications for heart-related conditions.
• Pregnancy and breastfeeding: Oxramet G may not be recommended during pregnancy or breastfeeding. Consult your healthcare provider for guidance.

Follow all the precautions and instructions provided by your healthcare provider to ensure safe and effective use of Oxramet G.

Storage

Oxramet G should be stored at room temperature, away from moisture and heat. Keep the medication in its original container with the lid tightly closed. Do not transfer the tablets to another container.

Keep Oxramet G out of reach of children and pets. If you have any unused or expired medication, dispose of it properly according to local guidelines or consult your pharmacist for guidance.

Patient Tips

• Take Oxramet G as directed: Follow your healthcare provider’s instructions regarding the dose and timing of this medication. Taking it at the same time each day can help maintain consistent blood sugar control.
• Monitor your blood sugar levels: Regularly check your blood sugar levels as directed by your healthcare provider. This can help you track your progress and make any necessary adjustments to your treatment plan.
• Maintain a healthy lifestyle: Oxramet G is part of a comprehensive treatment plan for type 2 diabetes. Follow a healthy diet, engage in regular exercise, and manage stress to optimize your overall health and well-being.
• Stay hydrated: Drink plenty of water throughout the day to maintain proper hydration, especially if you experience increased urination while taking Oxramet G.
• Attend regular check-ups: Keep up with your scheduled appointments with your healthcare provider to monitor your progress, discuss any concerns, and make any necessary adjustments to your treatment plan.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• About dapagliflozin (NHS UK) [Accessed 1 Jun. 2024] (online) Available at:
• Forxiga 10 mg film-coated tablets (Health Professionals SmPC) Available at:
• Dapagliflozin (Drugs.com) [Accessed 24 Jun. 2024] (online) Available at:
• dapagliflozin propaned 10 mg-metformin er 1,000 mg tablet,ext rel 24hr antihyperglycemic-sod/gluc cotransport-2 (sglt2) inhibitors (RX) [Accessed 23 Jun. 2024] (online) Available at:
• Dapagliflozin (MedlinePlus) [Accessed 25 Jun. 2024] (online) Available at:
• Dhillon S. Dapagliflozin: A Review in Type 2 Diabetes. Drugs. 2019 Jul;79(10):1135-1146. doi: 10.1007/s40265-019-01148-3. [Accessed 15 Jun. 2024] Available at: