Pafev-Thio Tablet

Introduction

Pafev-Thio is a prescription medication that contains three active ingredients: Thiocolchicoside, Aceclofenac, and Paracetamol. It is available in tablet form and is primarily used to relieve pain and inflammation associated with musculoskeletal conditions.

Uses

Pafev-Thio is prescribed to treat conditions such as muscle spasms, sprains, strains, and joint disorders. It is often used to alleviate pain and discomfort caused by conditions like arthritis, back pain, and sports injuries.

Dosage and Administration

The dosage of Pafev-Thio may vary depending on the severity of the condition and the individual patient. Follow the instructions provided by your healthcare professional or as indicated on the packaging. Typically, the recommended dosage for adults is one tablet taken orally, with or after meals, twice a day. It is important not to exceed the prescribed dosage.

Mechanism of Action

Thiocolchicoside, one of the active ingredients in Pafev-Thio, is a muscle relaxant that works by reducing muscle spasms and stiffness. Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that helps reduce pain and inflammation. Paracetamol, also known as acetaminophen, is a pain reliever and fever reducer. Together, these ingredients work synergistically to provide relief from pain, inflammation, and muscle spasms.

Side Effects

Common side effects may include nausea, stomach discomfort, headache, dizziness, and skin rash. If any of these side effects persist or worsen, consult your healthcare professional.

Serious side effects are rare but can occur. These may include severe allergic reactions, such as difficulty breathing, swelling of the face or throat, or rash. In some cases, Pafev-Thio may cause liver or kidney problems. If you experience any signs of liver or kidney dysfunction, such as yellowing of the skin or eyes, dark urine, or persistent abdominal pain, seek immediate medical attention.

Drug Interactions

Pafev-Thio may interact with certain medications, including anticoagulants (blood thinners), other NSAIDs, diuretics, and certain medications used to treat high blood pressure. Inform your healthcare professional about all the medications you are currently taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions.

Precautions

Before taking Pafev-Thio, inform your healthcare professional about any existing medical conditions, such as liver or kidney disease, stomach ulcers, asthma, or a history of allergic reactions to medications. Pafev-Thio is not recommended for use in individuals with a known hypersensitivity to any of its active ingredients.

Avoid consuming alcohol while taking Pafev-Thio, as it may increase the risk of liver damage. Additionally, this medication should be used with caution in elderly patients and individuals with a history of heart problems or high blood pressure. It is always best to consult your healthcare professional before starting any new medication.

Storage

Patient Tips

• Take Pafev-Thio as prescribed by your healthcare professional.
• If you experience any unusual or severe side effects, seek medical attention immediately.
• complete the full course of treatment, even if you start feeling better.
• Avoid activities that require mental alertness or coordination until you know how the medication affects you.
• Do not take Pafev-Thio if you are pregnant or breastfeeding, unless specifically instructed by your healthcare professional.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Paracetamol for adults: painkiller for pain and high temperature (NHS UK) [Accessed 17 Jun. 2024] (online) Available at:
• Aceclofenac 100 mg Film-coated Tablets (Health Professionals SmPC) Available at:
• ACECLOFENAC 100MG TABLETS (Drugs.com) [Accessed 11 Jun. 2024] (online) Available at:
• paracetamol tablet (OTC) [Accessed 9 Jun. 2024] (online) Available at:
• Acetaminophen Level: MedlinePlus Medical Test (MedlinePlus) [Accessed 23 Jun. 2024] (online) Available at: acetaminophen-level” rel=”noreferrer noopener” target=”_blank”>
• Negi S, Tandel N, Sharma P, Kumar R, Tyagi RK. Aceclofenac and methotrexate combination therapy could influence Th1/Th17 axis to modulate rheumatoid-arthritis-induced inflammation. Drug Discov Today. 2023 Aug;28(8):103671. doi: 10.1016/j.drudis.2023.103671. Epub 2023 Jun 16. [Accessed 25 Jun. 2024] Available at: