Paliris LA 75mg Injection

Introduction

Paliris LA is a prescription medication that contains the active ingredient Paliperidone. It is available in the form of an injectable solution and is primarily used to treat certain mental disorders.

Uses

Paliris LA is commonly prescribed for the treatment of schizophrenia, a chronic mental disorder characterized by abnormal thinking, emotional instability, and disorganized behavior. It can also be used to manage schizoaffective disorder, a condition that combines symptoms of both schizophrenia and mood disorders.

Dosage and Administration

The dosage and administration of Paliris LA should be determined by a healthcare professional, taking into consideration the individual’s condition, response to treatment, and other factors. It is typically administered as an intramuscular injection, usually once every four weeks. The injection site may vary, but it is commonly given in the deltoid muscle of the upper arm or the gluteal muscle in the buttocks.

Mechanism of Action

Paliperidone, the active ingredient in Paliris LA, belongs to a class of medications known as atypical antipsychotics. It works by modulating the activity of certain chemicals in the brain, particularly dopamine and serotonin, which are involved in regulating mood, thoughts, and behavior. By blocking specific receptors, Paliperidone helps to restore the balance of these neurotransmitters, reducing the symptoms associated with schizophrenia.

Side Effects

Common side effects may include drowsiness, dizziness, headache, constipation, and dry mouth. These side effects are usually mild and temporary.

However, be aware of the possibility of more serious side effects, such as extrapyramidal symptoms (movement disorders), neuroleptic malignant syndrome (a potentially life-threatening condition), and metabolic changes (such as increased blood sugar or cholesterol levels). If you experience any unusual or severe side effects, seek immediate medical attention.

Drug Interactions

Paliris LA may interact with other medications, including but not limited to other antipsychotics, certain antidepressants, and medications that affect the heart rhythm. Inform your healthcare professional about all the medications you are taking, including prescription, over-the-counter, and herbal products, to avoid any potential interactions. Your healthcare professional will be able to assess the risks and benefits of using Paliris LA in combination with other medications.

Precautions

Before starting treatment with Paliris LA, inform your healthcare professional about any pre-existing medical conditions, including liver or kidney problems, cardiovascular diseases, or a history of seizures. Additionally, disclose any allergies or sensitivities to medications.

Paliris LA should not be used in individuals who have a known hypersensitivity to Paliperidone or any of the other ingredients in the medication. It is also contraindicated in individuals with a history of neuroleptic malignant syndrome or who are in a comatose state.

Storage

Patient Tips

• attend all scheduled appointments with your healthcare professional to ensure proper monitoring and adjustment of your treatment.
• Avoid consuming alcohol while using Paliris LA, as it may increase the risk of side effects.
• If you miss a scheduled dose, contact your healthcare professional to determine the best course of action.
• Be cautious when engaging in activities that require mental alertness and coordination, as Paliris LA may cause drowsiness or dizziness.
• If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Paliris LA with your healthcare professional.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Byannli 1000mg prolonged-release suspension for injection in pre-filled syringe (Health Professionals SmPC) Available at:
• Paliperidone (Drugs.com) [Accessed 0 Jun. 2024] (online) Available at:
• paliperidone er (RX) [Accessed 4 Jun. 2024] (online) Available at:
• Paliperidone Injection (MedlinePlus) [Accessed 3 Jun. 2024] (online) Available at:
• Naguy A, Adel T, Almazeedi I. Paliperidone Use in Child Psychiatry: Evidence or Diffidence? Pharmacology. 2019;104(1-2):67-70. doi: 10.1159/000500629. Epub 2019 May 16. [Accessed 12 Jun. 2024] Available at: