Palochem 0.25mg Injection

Introduction

Palochem is a prescription medication that contains the active ingredient Palonosetron. It is available under the brand name Palochem. This medication is primarily used to prevent nausea and vomiting caused by certain chemotherapy treatments.

Uses

Palochem is prescribed to patients who are undergoing chemotherapy treatment to prevent nausea and vomiting. It is commonly used in patients receiving moderately or highly emetogenic chemotherapy, which are treatments known to cause significant nausea and vomiting.

Dosage and Administration

Palochem is administered by healthcare professionals as an intravenous (IV) infusion. The recommended dosage for adults is a single dose of 0.25 mg given over 30 seconds, approximately 30 minutes before the start of chemotherapy. The dosage may vary depending on the specific chemotherapy regimen and individual patient factors. Follow the instructions provided by your healthcare provider.

Mechanism of Action

Palonosetron, the active ingredient in Palochem, works by blocking the action of serotonin, a chemical in the body that can trigger nausea and vomiting. By inhibiting the serotonin receptors in the brain and gastrointestinal tract, Palonosetron helps to prevent chemotherapy-induced nausea and vomiting.

Side Effects

Common side effects may include headache, constipation, and fatigue. Note that not all patients will experience these side effects, and they may vary in severity. If you experience any persistent or bothersome side effects, it is recommended to consult your healthcare provider.

In rare cases, Palochem may cause serious side effects such as allergic reactions, irregular heartbeat, or changes in liver function. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Palochem may interact with other medications. Inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. Certain medications, such as apomorphine and medications that prolong the QT interval, may interact with Palochem and increase the risk of side effects. Your healthcare provider will assess the potential interactions and adjust your treatment plan accordingly.

Precautions

Before using Palochem, inform your healthcare provider about any known allergies, medical conditions, or medications you are taking. This medication may not be suitable for everyone, and your healthcare provider will assess the potential risks and benefits before prescribing it.

Palochem is contraindicated in patients with known hypersensitivity to Palonosetron or any of the other ingredients in the formulation. It should also be used with caution in patients with certain cardiac conditions or a history of irregular heartbeats.

Storage

Palochem should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of the reach of children and pets. Do not use the medication if it is past the expiration date or if the solution appears discolored or contains particles.

Patient Tips

• attend all scheduled chemotherapy appointments and follow your healthcare provider’s instructions regarding the use of Palochem.
• If you experience any unusual or severe side effects, contact your healthcare provider immediately.
• Maintain good hydration by drinking plenty of fluids, as this can help reduce the risk of nausea and vomiting.
• Follow a balanced diet and eat smaller, more frequent meals to help manage nausea and vomiting.
• If you have any concerns or questions about Palochem, don’t hesitate to reach out to your healthcare provider for clarification.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Akynzeo 300 mg/0.5 mg hard capsules (Health Professionals SmPC) Available at:
• Palonosetron injection (Drugs.com) [Accessed 1 Jun. 2024] (online) Available at:
• fosnetupitant-palonosetron solution, reconstituted (recon soln) (RX) [Accessed 22 Jun. 2024] (online) Available at:
• Palonosetron Injection (MedlinePlus) [Accessed 24 Jun. 2024] (online) Available at:
• Siddiqui MA, Scott LJ. Palonosetron. Drugs. 2004;64(10):1125-32; discussion 1133-4. doi: 10.2165/00003495-200464100-00006. [Accessed 29 Jun. 2024] Available at: