Panzol-D 30mg/40mg Capsule

Introduction

Panzol-D is a prescription medication that combines two active ingredients: Domperidone and Pantoprazole. Domperidone is a dopamine antagonist that helps regulate digestion and prevent nausea and vomiting. Pantoprazole belongs to a class of medications called proton pump inhibitors (PPIs) and helps reduce the production of stomach acid. Together, these ingredients work synergistically to provide relief from gastrointestinal symptoms.

Uses

Panzol-D is primarily prescribed for the following conditions:

• Gastroesophageal Reflux Disease (GERD): It is used to relieve symptoms such as heartburn, acid reflux, and regurgitation caused by the excessive production of stomach acid.
• Non-Ulcer Dyspepsia: It is used to manage symptoms such as bloating, discomfort, and early satiety in patients with indigestion.
• Gastroparesis: It is used to improve stomach emptying and alleviate symptoms such as nausea and vomiting in individuals with delayed gastric emptying.

Dosage and Administration

• The recommended dosage of Panzol-D is determined by your healthcare provider based on your specific condition and medical history.
• It is typically taken orally, with or without food. Swallow the capsule whole with a glass of water. Do not crush or chew the capsule.
• Follow your healthcare provider’s instructions regarding the dosage frequency and duration of treatment. Take the medication as prescribed for optimal results.

Mechanism of Action

Panzol-D works in two ways to provide relief from gastrointestinal symptoms. Domperidone acts as a dopamine antagonist, which helps regulate digestion by increasing the movement of food through the digestive system and preventing nausea and vomiting. Pantoprazole, on the other hand, is a proton pump inhibitor that reduces the production of stomach acid, providing relief from conditions caused by excess acid production.

Side Effects

Common side effects may include:

• Headache
• Dizziness
• Abdominal pain
• Diarrhea
• Nausea

If these side effects persist or worsen, consult your healthcare provider. In rare cases, Panzol-D may cause more serious side effects such as:

• Allergic reactions (rash, itching, swelling, difficulty breathing)
• Irregular heartbeat
• Muscle stiffness or tremors
• Severe abdominal pain

If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Panzol-D may interact with other medications and substances. Inform your healthcare provider about all the medications, supplements, and herbal products you are taking. Some common and serious drug interactions may include:

• Cisapride: Combining Panzol-D with cisapride may increase the risk of irregular heart rhythm.
• Warfarin: The use of Panzol-D with warfarin may increase the risk of bleeding.
• Antifungal medications: Certain antifungal medications may increase the concentration of Panzol-D in the blood, leading to an increased risk of side effects.

Follow your healthcare provider’s instructions and inform them of any changes in your medication regimen.

Precautions

Before taking Panzol-D, consider the following precautions:

• Inform your healthcare provider about any known allergies or hypersensitivity to Domperidone, Pantoprazole, or any other medications.
• Inform your healthcare provider about any medical conditions you have, especially liver disease or heart problems.
• Panzol-D may interact with other medications, so inform your healthcare provider about all the medications, supplements, and herbal products you are taking.
• If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before taking Panzol-D.

Storage

Store Panzol-D in a cool, dry place away from direct sunlight. Keep it out of the reach of children and pets. Do not use the medication after the expiration date printed on the packaging. If you have any unused or expired medication, consult your pharmacist or healthcare provider for proper disposal methods.

Patient Tips

• Take the medication exactly as prescribed by your healthcare provider. Do not exceed the recommended dosage or use it for a longer duration without medical supervision.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Avoid consuming alcohol while taking Panzol-D, as it may increase the risk of side effects.
• If you experience any unusual symptoms or have concerns while taking Panzol-D, do not hesitate to contact your healthcare provider for guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Domperidone: anti-sickness medicine for nausea and vomiting (NHS UK) [Accessed 10 Jun. 2024] (online) Available at:
• Domperidone 10 mg film-coated tablets (Health Professionals SmPC) Available at:
• Domperidone (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
• pantoprazole sodium (RX) [Accessed 11 Jun. 2024] (online) Available at:
• Definitions of Digestive Terms (International Foundation for Gastrointestinal Disorders) [Accessed 3 Jun. 2024] (online) Available at:
• Puoti MG, Assa A, Benninga M, Broekaert IJ, Carpi FJM, Deganello Saccomani M, Dolinsek J, Homan M, Mas E, Miele E, Tzivinikos C, Thomson M, Borrelli O. Drugs in Focus: Domperidone. J Pediatr Gastroenterol Nutr. 2023 Aug 1;77(2):e13-e22. doi: 10.1097/MPG.0000000000003822. Epub 2023 May 9. [Accessed 7 Jun. 2024] Available at: