Pegloose Tablet

Introduction

Pegloose is a medication that contains the active ingredient Prucalopride. It is available in tablet form and is commonly prescribed under the brand name Pegloose. This medication is primarily used to treat chronic constipation in adults who have not responded adequately to other laxatives.

Uses

Pegloose is used to relieve symptoms of chronic constipation. It helps to improve bowel movements and reduce the discomfort associated with infrequent or difficult bowel movements. This medication works by increasing the movement of the intestines, which helps to facilitate the passage of stools.

Dosage and Administration

The recommended dosage of Pegloose is usually one tablet (2 milligrams) taken orally once daily. Follow the instructions provided by your healthcare professional or as indicated on the product label. The tablet should be swallowed whole with a glass of water and can be taken with or without food. Do not crush or chew the tablet.

Mechanism of Action

Prucalopride, the active ingredient in Pegloose, is a selective serotonin type 4 receptor (5-HT4) agonist. It works by binding to the 5-HT4 receptors in the intestines, which stimulates the release of serotonin. This helps to increase the motility of the gastrointestinal tract, leading to improved bowel movements and relief from constipation.

Side Effects

Common side effects that may occur include headache, nausea, diarrhea, abdominal pain, and dizziness. If any of these side effects persist or worsen, consult your healthcare professional.

In rare cases, Pegloose may cause serious side effects such as severe abdominal pain, bloody stools, rectal bleeding, or signs of an allergic reaction (e.g., rash, itching, swelling). If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

inform your healthcare professional about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. Some medications may interact with Pegloose and affect its effectiveness or increase the risk of side effects. Common drug interactions include certain antidepressants, antipsychotics, and medications that affect heart rhythm. Your healthcare professional will be able to provide you with more specific information about potential drug interactions.

Precautions

Before taking Pegloose, inform your healthcare professional if you have a history of certain medical conditions, such as bowel obstruction, inflammatory bowel disease, or kidney problems. This medication may not be suitable for everyone, and your healthcare professional will assess the risks and benefits before prescribing it to you.

Pegloose should be used with caution in elderly patients and those with impaired liver function. It is not recommended for use in children or adolescents under 18 years of age.

Storage

Pegloose should be stored at room temperature, away from moisture and direct sunlight. Keep it out of reach of children and pets. Do not use this medication after the expiration date printed on the packaging.

Patient Tips

• Take Pegloose exactly as prescribed by your healthcare professional. Do not take more or less than the recommended dosage.
• If you forget to take a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
• It may take a few days or weeks for Pegloose to have a noticeable effect. Continue taking the medication as directed, even if you do not see immediate improvement.
• Maintain a healthy diet and lifestyle, including regular exercise and adequate fluid intake, to help manage constipation.
• If you have any questions or concerns about Pegloose, speak to your healthcare professional for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Prucalopride 1 mg film coated tablets (Health Professionals SmPC) Available at:
• Prucalopride (Drugs.com) [Accessed 22 Jun. 2024] (online) Available at:
• prucalopride tablet (RX) [Accessed 4 Jun. 2024] (online) Available at:
• Prucalopride (MedlinePlus) [Accessed 10 Jun. 2024] (online) Available at:
• [No authors listed] Prucalopride. 2020 Jul 20. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. [Accessed 11 Jun. 2024] Available at: