Permite 5 % Cream

Introduction

Permite is a topical medication that contains Permethrin as its active ingredient. Permethrin is an insecticide and acaricide that is used to treat various skin conditions caused by parasites such as scabies and head lice.

Uses

Permite is primarily prescribed for the treatment of scabies, a contagious skin infestation caused by the Sarcoptes scabiei mite. It is also effective in treating head lice, another common parasitic infestation that affects the scalp and hair.

Dosage and Administration

To use Permite, start by thoroughly washing and drying the affected area. Apply a thin layer of the cream to the entire body from the neck down, paying special attention to areas such as the folds of the skin, between the fingers and toes, and the genital area. Leave the cream on for a recommended duration, usually around 8 to 14 hours, and then rinse it off completely.

For the treatment of head lice, apply the cream to the scalp and hair, making sure to cover all areas. Leave it on for the recommended time, typically around 10 minutes, and then rinse it out thoroughly.

Follow the instructions provided by your healthcare professional and read the product label carefully for specific dosage and administration guidelines.

Mechanism of Action

Permethrin, the active ingredient in Permite, works by paralyzing and killing the parasites that cause scabies and head lice. It disrupts their nervous system, ultimately leading to their demise. By targeting these parasites, Permite helps to alleviate the symptoms associated with these infestations and promote healing.

Side Effects

While Common side effects may include mild itching, redness, or irritation at the application site. These side effects are usually temporary and should resolve on their own.

In rare cases, serious side effects such as severe allergic reactions, including rash, swelling, or difficulty breathing, may occur. If you experience any unusual or severe side effects, discontinue use of the cream and seek immediate medical attention.

Drug Interactions

Permite is primarily used topically, which reduces the risk of significant drug interactions. However, it is always important to inform your healthcare professional about all the medications, including over-the-counter drugs and supplements, that you are currently taking. They can provide guidance on potential interactions and ensure the safe use of Permite.

Precautions

Before using Permite, inform your healthcare professional if you have any known allergies to Permethrin or any other ingredients in the cream. Additionally, let your healthcare professional know if you are pregnant, breastfeeding, or have any underlying medical conditions.

Avoid contact with the eyes while applying Permite, as it may cause irritation. If accidental contact occurs, rinse the eyes thoroughly with water.

Storage

Patient Tips

• Follow the instructions provided by your healthcare professional and read the product label carefully before using Permite.
• Thoroughly wash and dry the affected area before applying the cream.
• Apply a thin layer of the cream to the entire affected area, ensuring complete coverage.
• Leave the cream on for the recommended duration and then rinse it off thoroughly.
• If using the cream for head lice, make sure to cover the entire scalp and hair.
• Avoid contact with the eyes and rinse thoroughly if accidental contact occurs.
• If you experience any unusual or severe side effects, discontinue use and seek medical attention.
• Store the cream at room temperature, away from direct sunlight and heat.
• Keep the cream out of the reach of children and pets.
• Do not use the cream if it has expired or shows signs of deterioration.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Permethrin 5% w/w Cream (Health Professionals SmPC) Available at:
• Permethrin topical (Drugs.com) [Accessed 26 Jun. 2024] (online) Available at:
• bl permethrin liquid (RX/OTC) [Accessed 23 Jun. 2024] (online) Available at:
• Permethrin Topical (MedlinePlus) [Accessed 4 Jun. 2024] (online) Available at:
• Rosumeck S, Nast A, Dressler C. Ivermectin and permethrin for treating scabies. Cochrane Database Syst Rev. 2018 Apr 2;4(4):CD012994. doi: 10.1002/14651858.CD012994. [Accessed 13 Jun. 2024] Available at: