Pexetrust 100mg Injection

Introduction

Pexetrust is a prescription medication that contains the active ingredient Pemetrexed. It is available in the form of an injection and is primarily used for the treatment of certain types of cancer.

Uses

Pexetrust is indicated for the treatment of malignant pleural mesothelioma, a type of cancer that affects the lining of the lungs and chest cavity. It is also used in combination with other medications to treat advanced non-small cell lung cancer.

Dosage and Administration

Pexetrust should be administered under the supervision of a healthcare professional experienced in the use of chemotherapy medications. The dosage and administration schedule may vary depending on the specific condition being treated and the patient’s individual factors. Follow the instructions provided by your healthcare provider. The medication is typically given intravenously over a specified period of time.

Mechanism of Action

Pemetrexed, the active ingredient in Pexetrust, belongs to a class of medications called antifolate antineoplastic agents. It works by inhibiting the enzymes involved in DNA and RNA synthesis, which are essential for the growth and reproduction of cancer cells. By interfering with these processes, Pemetrexed helps to slow down or stop the growth of cancer cells.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, fatigue, loss of appetite, and changes in taste. These side effects are usually temporary and may improve with time. However, if they persist or become bothersome. Inform your healthcare provider.

In some cases, Pexetrust may cause more serious side effects. These can include severe allergic reactions, decreased blood cell counts, liver problems, kidney problems, and lung problems. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Pexetrust may interact with other medications, including certain antibiotics, antifungal medications, and vaccines. Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Your healthcare provider can determine if any potential interactions exist and make appropriate adjustments to your treatment plan.

Precautions

Before using Pexetrust, inform your healthcare provider about any medical conditions you have, including kidney or liver problems, a history of heart disease, or any allergies. This medication may not be suitable for everyone, and your healthcare provider can help determine if it is the right option for you.

Pexetrust should not be used during pregnancy, as it may harm the developing fetus. Use effective contraception during treatment and for a certain period of time after the last dose. If you are breastfeeding, discuss the potential risks and benefits with your healthcare provider.

Storage

Pexetrust should be stored in a refrigerator between 2°C and 8°C (36°F and 46°F). Do not freeze the medication. Keep it in the original packaging and protect it from light. If the medication is not used within the recommended time period, it should be properly disposed of according to local regulations.

Patient Tips

• Follow the dosage and administration instructions provided by your healthcare provider.
• Stay hydrated and maintain a balanced diet to help manage potential side effects.
• Contact your healthcare provider if you experience any concerning or persistent side effects.
• Keep all scheduled appointments with your healthcare provider for monitoring and follow-up.
• Store the medication properly in the refrigerator and protect it from light.
• Dispose of any unused medication as directed by your healthcare provider or local regulations.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Alimta 100mg powder for concentrate for solution for infusion (Health Professionals SmPC) Available at:
• Pemetrexed (Drugs.com) [Accessed 22 Jun. 2024] (online) Available at:
• pemetrexed 25 mg/ml intravenous solution folate antagonists (RX) [Accessed 14 Jun. 2024] (online) Available at:
• Pemetrexed Injection (MedlinePlus) [Accessed 18 Jun. 2024] (online) Available at:
• Garassino MC, Gadgeel S, Speranza G, Felip E, Esteban E, Dómine M, Hochmair MJ, Powell SF, Bischoff HG, Peled N, Grossi F, Jennens RR, Reck M, Hui R, Garon EB, Kurata T, Gray JE, Schwarzenberger P, Jensen E, Pietanza MC, Rodríguez-Abreu D. Pembrolizumab Plus Pemetrexed and Platinum in Nonsquamous Non-Small-Cell Lung Cancer: 5-Year Outcomes From the Phase 3 KEYNOTE-189 Study. J Clin Oncol. 2023 Apr 10;41(11):1992-1998. doi: 10.1200/JCO.22.01989. Epub 2023 Feb 21. [Accessed 7 Jun. 2024] Available at: