Pioz 15 Tablet

Introduction

Pioz is a prescription medication that contains the active ingredient Pioglitazone. It is available under the brand name Pioz. This medication is primarily used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Uses

Pioz is prescribed to treat type 2 diabetes mellitus. It helps to control blood sugar levels by improving the body’s sensitivity to insulin and reducing the amount of glucose produced by the liver.

Dosage and Administration

The dosage of Pioz will vary depending on individual needs and the advice of the healthcare provider. It is usually taken once daily, with or without food. Follow the prescribed dosage and administration instructions provided by your healthcare professional.

Mechanism of Action

Pioglitazone, the active ingredient in Pioz, belongs to a class of medications called thiazolidinediones. It works by activating certain receptors in the body called peroxisome proliferator-activated receptors (PPARs). By activating these receptors, Pioglitazone helps improve insulin sensitivity in the body’s cells, leading to better control of blood sugar levels.

Side Effects

Common side effects may include:

• Edema (fluid retention)
• Weight gain
• Headache
• Hypoglycemia (low blood sugar)
• Upper respiratory tract infection

Serious side effects are rare but can occur. If you experience any of the following serious side effects, contact your healthcare provider immediately:

• Blurred vision or other changes in vision
• Shortness of breath or difficulty breathing
• Chest pain
• Yellowing of the skin or eyes (jaundice)
• Dark urine or pale stools

note that this is not a complete list of side effects. If you experience any unexpected or bothersome side effects while taking Pioz, consult your healthcare provider.

Drug Interactions

Pioz may interact with other medications. Inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. Some common drug interactions with Pioz include:

• Insulin or other oral antidiabetic medications
• Gemfibrozil (a medication used to lower cholesterol)
• Rifampin (an antibiotic)
• Certain heart medications such as nifedipine and digoxin

follow your healthcare provider’s instructions regarding medication interactions and to report any new medications you start taking while using Pioz.

Precautions

Before starting Pioz, inform your healthcare provider about any medical conditions you have, especially:

• Heart failure or a history of heart problems
• Liver disease
• Bladder cancer or a history of bladder cancer
• Edema (fluid retention)

Pioz may not be suitable for everyone, and there may be certain contraindications or precautions to consider. Your healthcare provider will assess your individual circumstances and determine if Pioz is appropriate for you.

Storage

Patient Tips

• Take Pioz as prescribed by your healthcare provider. Do not change the dosage or stop taking the medication without consulting your healthcare provider.
• Follow a healthy diet and exercise regularly while using Pioz to maximize its effectiveness.
• Monitor your blood sugar levels regularly as directed by your healthcare provider.
• If you experience any concerning or persistent side effects, contact your healthcare provider.
• Attend regular check-ups with your healthcare provider to monitor your progress and discuss any concerns.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Pioglitazone: medicine to treat type 2 diabetes (NHS UK) [Accessed 12 Jun. 2024] (online) Available at:
• Competact 15 mg/850 mg film-coated tablets (Health Professionals SmPC) Available at:
• Pioglitazone (Drugs.com) [Accessed 8 Jun. 2024] (online) Available at:
• alogliptin-pioglitazone (RX) [Accessed 19 Jun. 2024] (online) Available at:
• Pioglitazone (MedlinePlus) [Accessed 15 Jun. 2024] (online) Available at:
• DeFronzo RA, Inzucchi S, Abdul-Ghani M, Nissen SE. Pioglitazone: The forgotten, cost-effective cardioprotective drug for type 2 diabetes. Diab Vasc Dis Res. 2019 Mar;16(2):133-143. doi: 10.1177/1479164118825376. Epub 2019 Feb 1. [Accessed 26 Jun. 2024] Available at: