Pregdot 5mg Tablet

Introduction

Pregdot, containing the active ingredient Allylestrenol, is a prescription medication used for various medical conditions. It is available under the brand name Pregdot.

Uses

Pregdot is primarily prescribed to treat conditions related to hormonal imbalances, such as threatened miscarriage, recurrent pregnancy loss, and inadequate corpus luteum function. It may also be used in the management of certain hormonal disorders in women.

Dosage and Administration

The dosage and administration of Pregdot should be determined by your healthcare professional based on your specific medical condition and response to treatment. Follow their instructions carefully. Typically, the recommended dose for adults is 5 to 10 milligrams (mg) taken orally, two to three times a day. However, individual dosages may vary, so it’s crucial to consult your doctor for personalized guidance.

Mechanism of Action

Allylestrenol, the active ingredient in Pregdot, is a synthetic progestogen hormone. It functions by supporting the development and maintenance of the uterine lining, thereby promoting a favorable environment for a healthy pregnancy. It may also have immunomodulatory effects that help prevent certain pregnancy complications.

Side Effects

Common side effects may include nausea, vomiting, dizziness, or breast tenderness. These are generally mild and should resolve on their own. However, if any of these symptoms persist or worsen, it is advisable to consult your healthcare provider.

Serious side effects are rare but can occur. These may include allergic reactions, such as rash, itching, swelling, or difficulty breathing. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

inform your healthcare professional about all medications you are currently taking, including prescription, over-the-counter, and herbal products. Certain medications may interact with Pregdot, potentially affecting its effectiveness or increasing the risk of side effects. Common drug interactions may occur with medications such as anticoagulants, corticosteroids, or other hormonal therapies. Always consult your doctor or pharmacist before starting or stopping any medication while taking Pregdot.

Precautions

Before taking Pregdot, disclose your complete medical history, including any allergies, existing medical conditions, or prior adverse reactions to medications. This information will help your healthcare provider assess the suitability and safety of the medication for you.

Pregdot is contraindicated in individuals who are hypersensitive to Allylestrenol or any other ingredients in the formulation. Note that this medication is specifically intended for use in women and should not be used by men or children.

Be cautious when using Pregdot if you have a history of blood clotting disorders, liver dysfunction, or any other significant medical condition. Your healthcare provider will monitor your progress closely while you are taking this medication.

Storage

Pregdot should be stored at room temperature, away from direct sunlight and moisture. Ensure that it is kept out of reach of children and pets. Do not use the medication if it has expired or shows any signs of degradation.

Patient Tips

To ensure the safe and effective use of Pregdot, consider the following tips:

• Take the medication exactly as prescribed by your healthcare provider.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• If you suspect an overdose, seek immediate medical attention or contact a poison control center.
• Inform your healthcare provider about any new or unusual symptoms that develop during the course of treatment.
• Attend regular follow-up appointments with your doctor to monitor your progress and discuss any concerns or questions you may have.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Yu Y, Yu T, Ding W, Xiu Y, Zhao M, Sun K, Zhang Q, Xu X. Evaluation of allylestrenol for clinical pregnancies in patients treated with assisted reproductive techniques: a retrospective, propensity score matched, observational study. BMC Pregnancy Childbirth. 2023 Sep 13;23(1):660. doi: 10.1186/s12884-023-05970-2. [Accessed 27 Jun. 2024] Available at:
• MADJEREK Z, DE VISSER J, VAN DER VIES J, OVERBEEK GA. Allylestrenol, a pregnancy maintaining oral gestagen. Acta Endocrinol (Copenh). 1960 Sep;35:8-19. doi: 10.1530/acta.0.xxxv0008. [Accessed 24 Jun. 2024] Available at:
• Czeizel A, Huiskes N. A case-control study to evaluate the risk of congenital anomalies as a result of allylestrenol therapy during pregnancy. Clin Ther. 1988;10(6):725-39. [Accessed 4 Jun. 2024] Available at:
• Bergink EW, Loonen PB, Kloosterboer HJ. Receptor binding of allylestrenol, a progestagen of the 19-nortestosterone series without androgenic properties. J Steroid Biochem. 1985 Aug;23(2):165-8. doi: 10.1016/0022-4731(85)90232-8. [Accessed 27 Jun. 2024] Available at: