Pregeb D 75/30 Capsule

Introduction

Pregeb D is a prescription medication that combines the active ingredients Pregabalin and Duloxetine. Pregabalin is an anticonvulsant drug, while Duloxetine is an antidepressant. This combination medication is primarily used to treat certain types of neuropathic pain, which is caused by nerve damage, as well as generalized anxiety disorder.

Uses

Pregeb D is prescribed to manage neuropathic pain associated with conditions such as diabetic peripheral neuropathy, postherpetic neuralgia, and fibromyalgia. It is also indicated for the treatment of generalized anxiety disorder.

Dosage and Administration

The dosage of Pregeb D will vary depending on the specific condition being treated and the individual patient. Follow the instructions provided by your healthcare professional. Typically, the recommended starting dose is one capsule taken orally once daily. However, your doctor may adjust the dosage based on your response to the medication.

Mechanism of Action

Pregeb D works by targeting the nerves in the body that are involved in pain transmission. Pregabalin binds to certain calcium channels in the central nervous system, which reduces the release of neurotransmitters that contribute to pain signals. Duloxetine, on the other hand, increases the levels of certain chemicals in the brain that help regulate mood and reduce pain.

Side Effects

Common side effects may include dizziness, drowsiness, dry mouth, constipation, and nausea. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, such as suicidal thoughts, unusual bleeding, or allergic reactions, seek medical attention immediately.

Drug Interactions

Pregeb D may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. Inform your healthcare professional about all the medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins. Some common medications that may interact with Pregeb D include monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), and certain pain medications.

Precautions

Before taking Pregeb D, inform your doctor about any existing medical conditions, especially if you have a history of liver or kidney problems, glaucoma, or seizures. This medication may not be suitable for everyone, and your doctor will need to evaluate the potential risks and benefits before prescribing it. Avoid alcohol while taking Pregeb D, as it may increase the risk of certain side effects.

Storage

Pregeb D should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Follow the dosage instructions provided by your healthcare professional.
• Take the medication at the same time each day to help maintain a consistent level of the drug in your body.
• It may take some time for Pregeb D to reach its full effect. Be patient and continue taking the medication as prescribed.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not stop taking Pregeb D without consulting your doctor, as sudden discontinuation may lead to withdrawal symptoms.
• If you have any questions or concerns about the medication, don’t hesitate to reach out to your healthcare professional for clarification.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Duloxetine: medicine to treat depression and anxiety (NHS UK) [Accessed 23 Jun. 2024] (online) Available at:
• Cymbalta 30mg hard gastro-resistant capsules (Health Professionals SmPC) Available at:
• Duloxetine (Drugs.com) [Accessed 7 Jun. 2024] (online) Available at:
• duloxetine 60 mg capsule,delayed release sprinkle (RX) [Accessed 12 Jun. 2024] (online) Available at:
• Duloxetine (MedlinePlus) [Accessed 15 Jun. 2024] (online) Available at:
• Migliorini F, Maffulli N, Eschweiler J, Baroncini A, Bell A, Colarossi G. Duloxetine for fibromyalgia syndrome: a systematic review and meta-analysis. J Orthop Surg Res. 2023 Jul 17;18(1):504. doi: 10.1186/s13018-023-03995-z. [Accessed 8 Jun. 2024] Available at: