Preswin 1 GM Injection

Introduction

Preswin is a prescription medication that contains the active ingredient Terlipressin. Terlipressin is a synthetic analogue of vasopressin, a hormone that plays a key role in regulating blood pressure and fluid balance in the body.

Uses

Preswin is primarily used to treat hepatorenal syndrome, a serious complication of advanced liver disease. It is also prescribed for the management of bleeding esophageal varices, a condition characterized by the presence of enlarged veins in the esophagus that can lead to severe bleeding.

Dosage and Administration

Preswin is administered by a healthcare professional as an intravenous infusion. The dosage and duration of treatment will vary depending on the individual patient’s condition and response to therapy. Follow the instructions provided by your healthcare provider.

Mechanism of Action

Terlipressin, the active ingredient in Preswin, works by constricting blood vessels in the abdominal organs, including the liver. This helps to improve blood flow to the kidneys and decrease the pressure in the portal vein, which is often elevated in liver disease. By reducing portal vein pressure, Terlipressin can help improve kidney function and decrease the risk of bleeding from esophageal varices.

Side Effects

Common side effects may include headache, nausea, abdominal pain, and changes in blood pressure. Notify your healthcare provider if these side effects persist or worsen.

Serious side effects of Preswin may include allergic reactions, chest pain, irregular heartbeat, and changes in mental status. If you experience any of these symptoms, seek immediate medical attention.

Drug Interactions

Preswin may interact with certain medications, including beta-blockers, which are commonly used to treat high blood pressure and heart conditions. Inform your healthcare provider about all medications you are taking, including over-the-counter drugs and herbal supplements, before starting treatment with Preswin.

Precautions

Before using Preswin, inform your healthcare provider about any allergies, medical conditions, or medications you are currently taking. Preswin may not be suitable for everyone, and your healthcare provider will assess the risks and benefits of treatment in your individual case.

Preswin should not be used in patients with a known allergy to Terlipressin or any other ingredients in the medication. It is also contraindicated in patients with certain heart conditions, uncontrolled high blood pressure, or active arterial bleeding.

Storage

Preswin should be stored in a cool and dry place, away from direct sunlight. It should be kept out of the reach of children and pets. Do not freeze the medication. Proper storage helps to maintain the stability and effectiveness of the product.

Patient Tips

• Follow the dosage instructions provided by your healthcare provider and do not exceed the recommended dose.
• If you miss a dose, contact your healthcare provider for guidance on when to take the next dose.
• Attend all scheduled appointments with your healthcare provider for monitoring and evaluation of your response to treatment.
• If you experience any unusual symptoms or side effects while using Preswin, contact your healthcare provider immediately.
• Store the medication as directed and dispose of any unused medication properly.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Glypressin 0.12mg/ml Solution for Injection (Health Professionals SmPC) Available at:
• Terlipressin (Drugs.com) [Accessed 30 Jun. 2024] (online) Available at:
• Wong F, Pappas SC, Curry MP, Reddy KR, Rubin RA, Porayko MK, Gonzalez SA, Mumtaz K, Lim N, Simonetto DA, Sharma P, Sanyal AJ, Mayo MJ, Frederick RT, Escalante S, Jamil K; CONFIRM Study Investigators. Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome. N Engl J Med. 2021 Mar 4;384(9):818-828. doi: 10.1056/NEJMoa2008290. [Accessed 17 Jun. 2024] Available at:
• Terlipressin Alternatives Compared (Drugs.com) [Accessed 0 Jun. 2024] (online) Available at: