Introduction
Provanol Plus is a prescription medication that combines two active ingredients: Propranolol and Flunarizine. Propranolol belongs to a class of drugs known as beta blockers, while Flunarizine is a calcium channel blocker. Provanol Plus is primarily used for the prevention and treatment of migraines and certain types of headaches.
Uses
Provanol Plus is prescribed to individuals who experience frequent migraines or headaches. It can help reduce the frequency and severity of migraine attacks and alleviate associated symptoms such as headache, nausea, and sensitivity to light and sound. This medication may also be used to prevent certain types of headaches, such as tension headaches.
Dosage and Administration
The dosage of Provanol Plus will vary depending on the individual and their specific condition. Follow the instructions provided by your healthcare professional. Generally, the recommended starting dose for adults is one tablet per day, taken orally with or without food. Your doctor may adjust the dosage based on your response to the medication. Take the medication at the same time each day to maintain consistent levels in your body.
Mechanism of Action
Provanol Plus works by blocking certain receptors in the body. Propranolol, a beta blocker, reduces the effects of adrenaline, thereby decreasing the heart rate and blood pressure. Flunarizine, a calcium channel blocker, works by preventing calcium from entering certain cells in the blood vessels, which helps to relax and widen the blood vessels. By combining these two mechanisms of action, Provanol Plus helps to prevent migraines and headaches.
Side Effects
Common side effects may include dizziness, fatigue, nausea, and stomach upset. These side effects are generally mild and temporary. However, if you experience any severe or persistent side effects such as difficulty breathing, chest pain, or swelling of the face or throat, seek medical attention immediately.
Drug Interactions
Provanol Plus may interact with other medications, including certain antidepressants, antihypertensives, and medications that affect heart rhythm. Inform your healthcare professional about all the medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins. They can determine if any potential interactions may occur and adjust your treatment plan accordingly.
Precautions
Before taking Provanol Plus, inform your healthcare professional about any existing medical conditions or allergies you may have. This medication may not be suitable for individuals with certain heart conditions, asthma, or liver problems. Avoid alcohol while taking Provanol Plus, as it may increase the risk of side effects. Additionally, this medication may cause drowsiness, so it is advised to use caution when driving or operating machinery.
Storage
Provanol Plus should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.
Patient Tips
- Take Provanol Plus regularly as prescribed by your healthcare professional, even if you are not experiencing migraines or headaches.
- If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- Do not abruptly stop taking Provanol Plus without consulting your doctor, as it may lead to a rebound effect or other withdrawal symptoms.
- Keep a record of your migraine attacks and any associated triggers or patterns. This can help you and your healthcare professional identify potential triggers and develop strategies to manage your migraines effectively.
- If you have any questions or concerns about Provanol Plus, reach out to your healthcare professional for further guidance and support.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Propranolol: medicine for heart problems, anxiety and migraine (NHS UK) [Accessed 3 Jun. 2024] (online) Available at:
- Bedranol 160mg SR Capsules (Health Professionals SmPC) Available at:
- Flunarizine (International database) (Drugs.com) [Accessed 24 Jun. 2024] (online) Available at:
- propranolol (RX) [Accessed 5 Jun. 2024] (online) Available at:
- LactMed: Drugs and Lactation Database (National Library of Medicine) [Accessed 1 Jun. 2024] (online) Available at:
- Deligianni CI, Sacco S, Ekizoglu E, Uluduz D, Gil-Gouveia R, MaassenVanDenBrink A, Ornello R, Sanchez-Del-Rio M, Reuter U, Versijpt J, de Vries T, Hussain M, Zeraatkar D, Lampl C. European Headache Federation (EHF) critical re-appraisal and meta-analysis of oral drugs in migraine prevention-part 2: flunarizine. J Headache Pain. 2023 Sep 19;24(1):128. doi: 10.1186/s10194-023-01657-3. [Accessed 0 Jun. 2024] Available at:
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