Ramistar-AM 5 Tablet

Introduction

Ramistar-AM is a prescription medication that combines two active ingredients: Amlodipine and Ramipril. Amlodipine belongs to a class of drugs known as calcium channel blockers, while Ramipril is an angiotensin-converting enzyme (ACE) inhibitor. This medication is commonly prescribed to help manage high blood pressure (hypertension) in adults.

Uses

Ramistar-AM is primarily used to treat high blood pressure. It can be prescribed as an initial treatment or in combination with other medications to help lower blood pressure and reduce the risk of cardiovascular events, such as heart attacks and strokes. By relaxing and widening the blood vessels, Amlodipine and Ramipril help to improve blood flow and decrease the workload on the heart.

Dosage and Administration

The dosage of Ramistar-AM will be determined by your healthcare provider based on your specific medical condition and other factors. Follow their instructions carefully. The medication is typically taken once a day, preferably at the same time each day. It can be taken with or without food.

To use the Ramistar-AM:

Shake the bottle well before each use.

Spray the prescribed dose directly into your mouth, aiming for the inside of your cheek.

Swallow the medication without chewing. You may drink water afterwards if needed.

Mechanism of Action

Amlodipine, one of the active ingredients in Ramistar-AM, works by blocking the entry of calcium into the smooth muscle cells lining the blood vessels. This results in the relaxation and widening of the blood vessels, reducing blood pressure and improving blood flow. Ramipril, on the other hand, inhibits the production of a hormone called angiotensin II, which causes blood vessels to narrow. By inhibiting this hormone, Ramipril helps to further lower blood pressure and improve cardiovascular function.

Side Effects

Common side effects may include dizziness, headache, swelling in the ankles or feet, flushing, and a persistent dry cough. These side effects are usually mild and transient, but if they persist or worsen, consult your healthcare provider.

Serious side effects are rare but may include allergic reactions, severe dizziness, fainting, irregular heartbeat, and signs of liver problems (such as yellowing of the eyes or skin, dark urine, or persistent nausea). If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Ramistar-AM may interact with other medications, including over-the-counter drugs and herbal supplements. Inform your healthcare provider about all the medications you are currently taking to avoid potential interactions. Some common drug interactions include:

• Potassium-sparing diuretics: Taking Ramistar-AM with potassium-sparing diuretics may increase the risk of high potassium levels in the blood.
• Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs, such as ibuprofen or naproxen, may reduce the effectiveness of Amlodipine.
• Lithium: Combining Ramistar-AM with lithium may increase the risk of lithium toxicity.

This is not an exhaustive list of drug interactions, so consult your healthcare provider or pharmacist for a complete understanding of potential interactions.

Precautions

Before taking Ramistar-AM, inform your healthcare provider about any medical conditions you have, especially if you have a history of liver disease, kidney disease, heart disease, diabetes, or angioedema. Additionally, inform your healthcare provider about any allergies you have to medications or other substances.

Certain precautions and contraindications may apply to the use of Ramistar-AM, and your healthcare provider will assess whether this medication is suitable for you. Follow their guidance and inform them of any changes in your health status.

Storage

Ramistar-AM should be stored at room temperature, away from excessive heat and moisture. Keep the bottle tightly closed when not in use. Do not store it in the bathroom or near the kitchen sink. Keep it out of reach of children and pets.

Patient Tips

• Take Ramistar-AM exactly as prescribed by your healthcare provider. Do not change the dosage or stop taking it without consulting them.
• It may take several weeks for Ramistar-AM to effectively lower your blood pressure. Keep taking it regularly, even if you feel well.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
• Avoid consuming grapefruit or grapefruit juice while taking Ramistar-AM, as it may increase the levels of the medication in your blood.
• If you have any questions or concerns about Ramistar-AM, reach out to your healthcare provider or pharmacist for clarification. They are there to help you navigate your treatment safely and effectively.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Amlodipine: a medicine to treat high blood pressure (NHS UK) [Accessed 24 Jun. 2024] (online) Available at:
• Amlodipine / Valsartan 10 mg / 160 mg film-coated tablets (Health Professionals SmPC) Available at:
• Amlodipine (Drugs.com) [Accessed 13 Jun. 2024] (online) Available at:
• amlodipine (RX) [Accessed 22 Jun. 2024] (online) Available at:
• Amlodipine (MedlinePlus) [Accessed 24 Jun. 2024] (online) Available at:
• van Zwieten PA. Amlodipine: an overview of its pharmacodynamic and pharmacokinetic properties. Clin Cardiol. 1994 Sep;17(9 Suppl 3):III3-6. [Accessed 6 Jun. 2024] Available at: