Ranolaz OD Tablet ER

Introduction

Ranolaz OD ER is a prescription medication that contains the active ingredient Ranolazine. It is available under the brand name Ranolaz OD ER. This medication is primarily used to treat chronic angina, a condition characterized by chest pain or discomfort caused by reduced blood flow to the heart muscle. Ranolaz OD ER helps to improve blood flow to the heart and reduce the frequency of angina episodes.

Uses

Ranolaz OD ER is prescribed to manage chronic angina in adult patients. It is used as an add-on therapy when other medications, such as beta-blockers or calcium channel blockers, are not providing sufficient relief or are not well-tolerated. Chronic angina is a long-term condition that requires ongoing treatment to control symptoms and improve quality of life. This medication helps to reduce the frequency of angina attacks and improve exercise tolerance.

Dosage and Administration

The dosage of Ranolaz OD ER may vary depending on the individual patient’s condition and response to treatment. Follow the instructions provided by your healthcare professional. Typically, the recommended starting dose is 500 mg, taken orally twice daily with or without food. Your doctor may adjust the dosage based on your specific needs. It is important not to crush, chew, or break the tablets, as they are designed to be taken whole. If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Mechanism of Action

Ranolaz OD ER works by inhibiting a specific sodium channel in the heart muscle. This action helps to reduce the accumulation of intracellular calcium and decrease the oxygen demand of the heart. By improving blood flow to the heart and reducing oxygen demand, Ranolaz OD ER helps to alleviate the symptoms of chronic angina and improve exercise tolerance.

Side Effects

Common side effects may include dizziness, headache, constipation, nausea, and abnormal heart rhythm. These side effects are usually mild and temporary. However, if you experience any persistent or severe side effects, contact your healthcare provider. In rare cases, Ranolaz OD ER may cause serious side effects such as liver problems, allergic reactions, or worsening heart failure. If you experience any signs of these serious side effects, such as yellowing of the skin or eyes, difficulty breathing, or swelling of the legs, seek immediate medical attention.

Drug Interactions

Ranolaz OD ER may interact with other medications, including certain antibiotics, antifungal drugs, and medications that affect the heart rhythm. Inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. They can assess the potential for drug interactions and adjust your treatment plan if necessary. It is particularly important to avoid taking Ranolaz OD ER with drugs that can prolong the QT interval, as this can increase the risk of abnormal heart rhythm.

Precautions

Before starting treatment with Ranolaz OD ER, inform your healthcare provider about any medical conditions you have, especially liver or kidney problems. This medication may not be suitable for individuals with certain pre-existing conditions or those taking specific medications. Ranolaz OD ER should not be used in patients with a known hypersensitivity to Ranolazine or any of its ingredients. It is also not recommended for use during pregnancy or while breastfeeding. Discuss all potential risks and benefits with your healthcare provider before starting treatment.

Storage

Ranolaz OD ER should be stored at room temperature, away from moisture and heat. Keep the medication in its original container with the lid tightly closed. Do not transfer the tablets to a different container. Keep it out of reach of children and pets. If you have any expired or unused tablets, consult your pharmacist or healthcare provider for proper disposal.

Patient Tips

• Take Ranolaz OD ER exactly as prescribed by your healthcare provider. Do not change the dosage or stop taking the medication without consulting them first.
• continue taking your other prescribed medications for angina unless instructed otherwise by your healthcare provider.
• If you experience any new or worsening symptoms while taking Ranolaz OD ER, inform your healthcare provider promptly.
• Avoid consuming grapefruit or grapefruit juice while taking Ranolaz OD ER, as it may increase the levels of the medication in your blood.
• Follow a healthy lifestyle, including regular exercise, a balanced diet, and stress management, to complement the effects of Ranolaz OD ER in managing chronic angina.
• If you have any questions or concerns about Ranolaz OD ER or your treatment plan, consult your healthcare provider for further guidance. They are best equipped to address your specific needs and provide personalized advice.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Ranexa 375 mg prolonged-release Tablets (Health Professionals SmPC) Available at:
• Ranolazine (Drugs.com) [Accessed 27 Jun. 2024] (online) Available at:
• ranolazine er (RX) [Accessed 12 Jun. 2024] (online) Available at:
• Ranolazine (MedlinePlus) [Accessed 0 Jun. 2024] (online) Available at:
• Kourampi I, Katsioupa M, Oikonomou E, Tsigkou V, Marinos G, Goliopoulou A, Katsarou O, Kalogeras K, Theofilis P, Tsatsaragkou A, Siasos G, Tousoulis D, Vavuranakis M. The Role of Ranolazine in Heart Failure-Current Concepts. Am J Cardiol. 2023 Dec 15;209:92-103. doi: 10.1016/j.amjcard.2023.09.066. Epub 2023 Oct 13. [Accessed 22 Jun. 2024] Available at: