Introduction
Rasuric is a prescription medication that contains the active ingredient Rasburicase. It is available under the brand name Rasuric. This medication is primarily used to manage high levels of uric acid in the blood, a condition known as hyperuricemia, which can occur in patients receiving treatment for certain types of cancer.
Uses
Rasuric is prescribed to prevent and treat tumor lysis syndrome (TLS) in patients undergoing chemotherapy for cancer. TLS is a potentially serious condition that can occur when cancer cells break down rapidly, releasing large amounts of uric acid into the bloodstream. Rasuric helps to lower and control uric acid levels, reducing the risk of related complications.
Dosage and Administration
Rasuric is administered by a healthcare professional through an intravenous (IV) infusion. The dosage and duration of treatment will vary depending on factors such as the patient’s weight, the specific chemotherapy regimen, and the extent of uric acid elevation. Your healthcare provider will determine the appropriate dose and frequency of administration for your individual needs.
Mechanism of Action
Rasburicase, the active ingredient in Rasuric, works by converting uric acid into a more soluble and easily excreted form called allantoin. By promoting the breakdown and elimination of uric acid, Rasburicase helps prevent the buildup of uric acid crystals in the body, reducing the risk of TLS and related complications.
Side Effects
Common side effects may include nausea, vomiting, diarrhea, headache, and fever. Note that these side effects are usually temporary and may resolve on their own. However, if these side effects persist or worsen, inform your healthcare provider.
In rare cases, Rasuric may cause serious side effects such as allergic reactions, including difficulty breathing, swelling of the face or throat, and severe rash. If you experience any of these symptoms, seek immediate medical attention.
Drug Interactions
inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Certain medications may interact with Rasuric, potentially affecting its effectiveness or increasing the risk of side effects. Your healthcare provider will carefully consider these potential interactions and adjust your treatment plan accordingly.
Precautions
Before starting treatment with Rasuric, inform your healthcare provider about any known allergies, medical conditions, or medications you are taking. This medication may not be suitable for individuals with a history of severe allergic reactions to rasburicase or any other ingredients in the formulation.
Rasuric should be used with caution in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency, as it may cause a temporary decrease in red blood cell count. Regular monitoring of blood counts and kidney function is recommended during treatment.
Storage
Rasuric should be stored in a cool, dry place, away from direct heat and sunlight. It should be kept out of the reach of children and pets. Do not freeze the medication, as this may affect its efficacy. If you have any unused or expired medication, consult your healthcare provider or pharmacist for proper disposal instructions.
Patient Tips
- Follow your healthcare provider’s instructions regarding the dosage and administration of Rasuric.
- Stay well-hydrated during treatment to promote the elimination of uric acid from your body.
- If you experience any unusual or persistent side effects, contact your healthcare provider promptly.
- Inform your healthcare provider about any other medications or supplements you are taking before starting Rasuric.
- Store Rasuric properly and safely, following the storage instructions provided.
- If you have any questions or concerns about your treatment with Rasuric, do not hesitate to consult your healthcare provider.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Rasburicase (Drugs.com) [Accessed 26 Jun. 2024] (online) Available at:
- rasburicase solution, reconstituted (recon soln) (RX) [Accessed 17 Jun. 2024] (online) Available at:
- Rasburicase Injection (MedlinePlus) [Accessed 7 Jun. 2024] (online) Available at:
- [No authors listed] Rasburicase. 2023 Nov 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. [Accessed 27 Jun. 2024] Available at:
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