Raxitinib 1mg Tablet

Introduction

Raxitinib is a prescription medication that contains the active ingredient Axitinib. It is available in tablet form and is prescribed for the treatment of certain types of advanced renal cell carcinoma, a type of kidney cancer.

Uses

Raxitinib is primarily used to treat advanced renal cell carcinoma. It is specifically prescribed for patients who have already undergone prior systemic therapy for their condition and require further treatment options.

Dosage and Administration

The dosage of Raxitinib may vary depending on individual factors such as the patient’s weight, overall health, and response to treatment. Follow your healthcare provider’s instructions regarding the dosage.

Generally, Raxitinib is taken orally, usually once daily. It is recommended to take the tablet at the same time each day, with or without food. Swallow the tablet whole with a glass of water, and do not crush, chew, or break it.

Mechanism of Action

Axitinib, the active ingredient in Raxitinib, belongs to a class of medications called tyrosine kinase inhibitors. It works by blocking the action of specific proteins in cancer cells, which helps to slow down the growth and spread of the cancer.

By inhibiting certain proteins, Axitinib helps to disrupt the signaling pathways that promote the growth of cancer cells. This can help to shrink tumors and slow down the progression of advanced renal cell carcinoma.

Side Effects

Common side effects may include fatigue, weakness, high blood pressure, decreased appetite, diarrhea, nausea, and vomiting.

Note that not all individuals will experience these side effects, and some may experience side effects that are not listed here. If you experience any unusual or persistent side effects while taking Raxitinib, contact your healthcare provider for further guidance.

In rare cases, Raxitinib may cause more serious side effects. These may include severe bleeding, heart problems, liver problems, thyroid problems, and gastrointestinal perforation. If you experience any severe or concerning side effects, seek immediate medical attention.

Drug Interactions

Raxitinib may interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. Inform your healthcare provider about all medications and supplements you are taking before starting Raxitinib.

Some medications that may interact with Raxitinib include strong CYP3A4 inhibitors, strong CYP3A4 inducers, and medications that affect blood clotting. These interactions can affect the effectiveness of Raxitinib or increase the risk of side effects.

Follow your healthcare provider’s advice and inform them of any changes in your medication regimen while taking Raxitinib.

Precautions

Before starting Raxitinib, inform your healthcare provider about any pre-existing medical conditions, including liver problems, bleeding disorders, and thyroid problems. This medication may not be suitable for individuals with certain medical conditions.

Raxitinib should not be used during pregnancy, as it may harm the unborn baby. If you are pregnant or planning to become pregnant, discuss the potential risks and benefits of Raxitinib with your healthcare provider.

Avoid grapefruit and grapefruit juice while taking Raxitinib, as it may increase the levels of the medication in your body and lead to an increased risk of side effects.

Storage

Raxitinib should be stored at room temperature, away from direct sunlight and moisture. Keep the medication in its original packaging, and ensure it is stored out of reach of children and pets.

Do not use Raxitinib if the packaging is damaged or if the tablets appear to be discolored or deteriorated. If you have any concerns about the storage or quality of your medication, consult your pharmacist for further guidance.

Patient Tips

• Follow your healthcare provider’s instructions regarding the dosage and timing of Raxitinib.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
• Do not take a double dose to make up for a missed dose.
• attend all scheduled appointments with your healthcare provider to monitor your response to Raxitinib and manage any potential side effects.
• If you have any questions or concerns about Raxitinib or its use, don’t hesitate to reach out to your healthcare provider for clarification.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Inlyta 1 mg film-coated tablets (Health Professionals SmPC) Available at:
• Axitinib (Drugs.com) [Accessed 6 Jun. 2024] (online) Available at:
• axitinib tablet (RX) [Accessed 26 Jun. 2024] (online) Available at:
• Axitinib (MedlinePlus) [Accessed 10 Jun. 2024] (online) Available at:
• Rini BI, Plimack ER, Stus V, Gafanov R, Hawkins R, Nosov D, Pouliot F, Alekseev B, Soulières D, Melichar B, Vynnychenko I, Kryzhanivska A, Bondarenko I, Azevedo SJ, Borchiellini D, Szczylik C, Markus M, McDermott RS, Bedke J, Tartas S, Chang YH, Tamada S, Shou Q, Perini RF, Chen M, Atkins MB, Powles T; KEYNOTE-426 Investigators. Pembrolizumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma. N Engl J Med. 2019 Mar 21;380(12):1116-1127. doi: 10.1056/NEJMoa1816714. Epub 2019 Feb 16. [Accessed 8 Jun. 2024] Available at: