Rebagen Tablet

Introduction

Rebagen is a medication that contains the active ingredient Rebamipide. It is available under the brand name Rebagen. This medication is primarily used to treat gastrointestinal disorders and promote healing of the gastric mucosa.

Uses

Rebagen is prescribed for the treatment of various conditions related to the gastrointestinal system. It is commonly used to manage gastric ulcers, gastritis, and other gastrointestinal disorders characterized by inflammation and mucosal damage. This medication works by protecting and enhancing the natural defense mechanisms of the stomach, promoting healing and reducing symptoms such as abdominal pain and discomfort.

Dosage and Administration

The recommended dosage of Rebagen may vary depending on the severity of the condition and the individual patient’s response. Follow the instructions provided by your healthcare professional. Generally, the usual adult dosage is one tablet taken three times a day, preferably before meals. The tablets should be swallowed whole with a glass of water, and it is advisable to avoid crushing or chewing them.

Mechanism of Action

Rebamipide, the active ingredient in Rebagen, works by increasing the secretion of protective substances in the stomach lining. It also stimulates the production of mucus and enhances blood flow to the gastric mucosa. These actions help to strengthen the natural defense mechanisms of the stomach, promoting the healing of ulcers and reducing inflammation.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, and abdominal discomfort. These side effects are usually mild and transient, and they typically resolve on their own without any specific treatment. However, if any of these side effects persist or worsen, consult your healthcare provider.

In rare cases, some individuals may experience more serious side effects such as allergic reactions, severe abdominal pain, or bleeding. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Rebagen may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. They can evaluate the potential interactions and adjust your treatment plan accordingly.

Precautions

Before starting Rebagen, inform your healthcare provider about any known allergies or sensitivities to medications. Additionally, provide a comprehensive medical history, including any previous gastrointestinal disorders or bleeding disorders.

Rebagen is contraindicated in individuals with a known hypersensitivity to Rebamipide or any of the other ingredients in the formulation. It should also be used with caution in individuals with a history of gastrointestinal bleeding or ulcers.

Storage

Rebagen should be stored in a cool, dry place away from direct sunlight. Be sure to keep it out of the reach of children and pets. Do not use the medication beyond its expiration date, as it may not be as effective.

Patient Tips

• Take the medication as prescribed by your healthcare provider, following the recommended dosage and schedule.
• It may take some time for the medication to show its full effects. Be patient and continue taking it as directed.
• If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Avoid consuming alcohol while taking Rebagen, as it may increase the risk of side effects.
• If you have any concerns or questions about your treatment, don’t hesitate to reach out to your healthcare provider for clarification.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Rebamipide (International database) (Drugs.com) [Accessed 30 Jun. 2024] (online) Available at:
• Bakulina NV, Tikhonov SV, Okovityi SV, Lutaenko EA, Bolshakov AO, Prikhodko VA, Nekrasova AS. [Pharmacokinetics and pharmacodynamics of rebamipide. New possibilities of therapy: A review]. Ter Arkh. 2023 Jan 16;94(12):1431-1437. doi: 10.26442/00403660.2022.12.202000. [Accessed 21 Jun. 2024] Available at:
• Zvyaglova MY, Knyazev OV, Parfenov AI. [Pharmacological and clinical feature of rebamipide: new therapeutic targets]. Ter Arkh. 2020 Apr 27;92(2):104-111. doi: 10.26442/00403660.2020.02.000569. [Accessed 0 Jun. 2024] Available at:
• Izawa T, Hutami IR, Tanaka E. Potential Role of Rebamipide in Osteoclast Differentiation and Mandibular Condylar Cartilage Homeostasis. Curr Rheumatol Rev. 2018 Apr 20;14(1):62-69. doi: 10.2174/1573397113666171017113441. [Accessed 20 Jun. 2024] Available at: