Retigraph 20% Injection

Introduction

Retigraph is a medication that contains the active ingredient Fluorescein. It is available in the form of an injectable solution.

Uses

Retigraph is primarily used as a diagnostic tool in ophthalmology. It is commonly employed to evaluate blood flow in the retina and choroid during angiography procedures. Additionally, it can help in the detection and monitoring of various ocular conditions, such as macular degeneration, diabetic retinopathy, and retinal vascular occlusion.

Dosage and Administration

Retigraph should be administered by a healthcare professional experienced in ophthalmic procedures. The dosage and administration may vary depending on the specific procedure being performed. The injection is usually given directly into a vein, and the dosage is determined based on the patient’s weight and individual needs.

Mechanism of Action

Fluorescein, the active ingredient in Retigraph, is a fluorescent dye that is injected into the bloodstream. It works by selectively binding to the vascular endothelium in the retina and choroid. When exposed to a specific wavelength of light, the dye fluoresces, allowing for visualization and assessment of blood flow in the ocular vessels. This information helps healthcare professionals diagnose and monitor various eye conditions.

Side Effects

Common side effects of Retigraph may include temporary discoloration of the skin and urine, as well as mild nausea or vomiting. These effects are usually transient and resolve on their own.

Serious side effects are rare but can include severe allergic reactions, such as difficulty breathing, swelling of the face or throat, and hives. If any of these symptoms occur, immediate medical attention should be sought.

Drug Interactions

There are no known significant drug interactions associated with Retigraph. However, it is always important to inform your healthcare provider about all the medications, supplements, and herbal products you are taking to ensure there are no potential interactions.

Precautions

Before using Retigraph, inform your healthcare provider about any known allergies to Fluorescein or any other dyes. Additionally, let your doctor know if you have any underlying medical conditions, especially kidney or liver disease.

Retigraph should be used with caution in pregnant or breastfeeding individuals, as there is limited information available on its safety in these populations.

Storage

Retigraph should be stored in a cool, dry place, away from direct sunlight and heat. It should be kept out of the reach of children and pets. Do not freeze the medication.

Patient Tips

• Follow all instructions provided by your healthcare professional regarding the administration of Retigraph.
• If you experience any unusual or persistent side effects, contact your healthcare provider immediately.
• It is normal for the skin and urine to temporarily appear yellow after receiving the injection. This discoloration is harmless and will resolve on its own.
• Make sure to inform your healthcare provider about any other medications or supplements you are taking before receiving Retigraph.
• Store the medication as directed and dispose of any unused solution properly.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• ANATERA 100mg/ml solution for injection (Health Professionals SmPC) Available at:
• Fluorescein (Drugs.com) [Accessed 26 Jun. 2024] (online) Available at:
• Fluorescein angiography (MedlinePlus) [Accessed 15 Jun. 2024] (online) Available at:
• S K, Sam B, George L, N SY, Varghese A. Fluorescein Based Fluorescence Sensors for the Selective Sensing of Various Analytes. J Fluoresc. 2021 Sep;31(5):1251-1276. doi: 10.1007/s10895-021-02770-9. Epub 2021 Jul 13. [Accessed 23 Jun. 2024] Available at: