Saligo 25mg/500mg Tablet

Introduction

Saligo is a prescription medication that contains the active ingredients Pyrimethamine and Sulphadoxine. It is available under the brand name Saligo. This medication is primarily used for the treatment and prevention of malaria, a mosquito-borne infectious disease.

Uses

Saligo is prescribed to individuals with malaria, a condition caused by the Plasmodium parasite. It is used to both treat active malaria infections and prevent future episodes of the disease in susceptible individuals. This medication is effective against certain strains of the malaria parasite.

Dosage and Administration

The dosage of Saligo will vary depending on factors such as the severity of the malaria infection, the patient’s age, and their overall health. Follow the instructions provided by your healthcare professional or the dosage guidelines on the product label.

Typically, the recommended dosage for adults and children is one tablet taken orally as a single dose. Take the medication with a full glass of water. Your healthcare professional may provide additional instructions based on your specific condition.

Mechanism of Action

Saligo contains two active ingredients, Pyrimethamine and Sulphadoxine, which work together to combat the malaria parasite. Pyrimethamine inhibits the growth and multiplication of the parasite by interfering with the production of essential components required for its survival. Sulphadoxine, on the other hand, targets the parasite’s ability to synthesize folic acid, which is crucial for its survival.

By targeting different aspects of the parasite’s life cycle, Saligo helps to effectively treat and prevent malaria infections.

Side Effects

Common side effects may include nausea, vomiting, stomach upset, headache, dizziness, and a rash. These side effects are usually mild and temporary.

In rare cases, serious side effects may occur. If you experience any of the following symptoms, seek immediate medical attention:

• Severe allergic reactions, such as difficulty breathing, swelling of the face or throat, or hives
• Blood disorders, such as anemia or low platelet count
• Liver problems, such as jaundice (yellowing of the skin or eyes), dark urine, or persistent fatigue
• Severe skin reactions, such as blistering or peeling

Drug Interactions

Saligo may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. Inform your healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements.

Some common drug interactions with Saligo include:

• Trimethoprim-sulfamethoxazole (a combination antibiotic)
• Methotrexate (a medication used in the treatment of certain cancers and autoimmune diseases)
• Phenytoin (an anticonvulsant medication)
• Warfarin (an anticoagulant medication)

discuss potential drug interactions with your healthcare professional before starting Saligo.

Precautions

Before taking Saligo, inform your healthcare professional about any allergies you may have, especially if you are allergic to Pyrimethamine, Sulphadoxine, or any other medications.

Certain precautions should be taken into consideration, including:

• Pregnancy and breastfeeding: Saligo should be used with caution during pregnancy and breastfeeding. Discuss the potential risks and benefits with your healthcare professional.
• Liver and kidney problems: Individuals with liver or kidney problems may require dosage adjustments or close monitoring while taking Saligo.
• G6PD deficiency: Saligo may cause a breakdown of red blood cells in individuals with G6PD deficiency. Discuss your medical history with your healthcare professional.

Storage

Saligo should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of the reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Take the medication exactly as prescribed by your healthcare professional.
• Complete the full course of treatment, even if you start to feel better.
• If you experience any side effects or have any concerns, contact your healthcare professional.
• Avoid taking any other medications or supplements without consulting your healthcare professional.
• If you are traveling to an area with a high risk of malaria, take appropriate preventive measures in addition to taking Saligo.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Pyrimethamine (Drugs.com) [Accessed 29 Jun. 2024] (online) Available at:
• pyrimethamine 25 mg tablet antimalarial drugs (RX) [Accessed 28 Jun. 2024] (online) Available at:
• Folic Acid (MedlinePlus) [Accessed 13 Jun. 2024] (online) Available at:
• Ramchandani S, Mohan CD, Mistry JR, Su Q, Naz I, Rangappa KS, Ahn KS. The multifaceted antineoplastic role of pyrimethamine against human malignancies. IUBMB Life. 2022 Mar;74(3):198-212. doi: 10.1002/iub.2590. Epub 2022 Jan 5. [Accessed 23 Jun. 2024] Available at: