Saphrine 1%/0.2% Ointment

Introduction

Saphrine is a prescription medication that contains two active ingredients: Sulfadiazine and Chlorhexidine Gluconate. It is used to treat various skin infections and help prevent the growth of bacteria on the skin’s surface.

Uses

Saphrine is commonly prescribed to treat skin conditions such as burns, wounds, and ulcers. It is particularly effective in preventing and treating infections caused by bacteria on the skin.

Dosage and Administration

The recommended dosage of Saphrine may vary depending on the severity of the infection and the specific instructions provided by your healthcare professional. Generally, it is applied topically to the affected area, following these steps:

Clean the affected area thoroughly with mild soap and water.

Pat the area dry with a clean towel.

Apply a thin layer of the ointment to cover the affected area.

Gently rub the ointment into the skin until it is evenly distributed.

Wash your hands after applying the ointment, unless your hands are the area being treated.

Follow the instructions provided by your healthcare professional and to use Saphrine for the prescribed duration of treatment.

Mechanism of Action

Saphrine combines the active ingredients Sulfadiazine and Chlorhexidine Gluconate, which work together to fight against bacterial infections. Sulfadiazine is a type of antibiotic that inhibits the growth and reproduction of bacteria, while Chlorhexidine Gluconate is an antiseptic that helps to kill bacteria on the skin’s surface.

By targeting both the growth and presence of bacteria, Saphrine helps to prevent the spread and growth of infection, promoting the healing process.

Side Effects

Common side effects may include mild skin irritation, redness, or itching at the application site. These side effects are usually temporary and subside on their own.

However, if you experience any severe or persistent side effects, such as severe skin irritation, rash, or swelling, seek medical attention and discontinue use of the ointment.

Drug Interactions

inform your healthcare professional about all the medications, including over-the-counter products and supplements, that you are currently taking. Certain medications may interact with Saphrine, potentially affecting its effectiveness or increasing the risk of side effects. Be sure to discuss any potential drug interactions with your healthcare professional.

Precautions

Before using Saphrine, inform your healthcare professional about any allergies you may have, especially to sulfonamide antibiotics. Additionally, let your healthcare professional know about any medical conditions you have, such as kidney or liver problems, as this may affect the safe use of the ointment.

Avoid contact with eyes, mouth, and other mucous membranes while applying the ointment. If accidental contact occurs, rinse thoroughly with water.

Storage

Saphrine should be stored at room temperature, away from direct sunlight and moisture. Keep the ointment out of reach of children and pets. Do not use the ointment if it has expired or if the packaging appears to be damaged.

Patient Tips

• Follow the dosage instructions provided by your healthcare professional and complete the full course of treatment, even if the symptoms improve.
• Avoid applying the ointment to open wounds or deep puncture wounds unless instructed by your healthcare professional.
• If you miss a dose, apply it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular application schedule.
• maintain good hygiene practices, such as washing your hands before and after applying the ointment.
• If you have any questions or concerns about your treatment with Saphrine, consult your healthcare professional for guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Chlorhexidine: antiseptic and disinfectant used for mouth ulcers, throat infections and skin infections (NHS UK) [Accessed 10 Jun. 2024] (online) Available at:
• Acriflex 0.25% w/w Cream (Health Professionals SmPC) Available at:
• Chlorhexidine topical (Drugs.com) [Accessed 19 Jun. 2024] (online) Available at:
• chlorhexidine gluconate mouthwash (RX) [Accessed 11 Jun. 2024] (online) Available at:
• Mouth sores (MedlinePlus) [Accessed 2 Jun. 2024] (online) Available at:
• Reynolds SS, Woltz P, Keating E, Neff J, Elliott J, Hatch D, Yang Q, Granger BB. Results of the CHlorhexidine Gluconate Bathing implementation intervention to improve evidence-based nursing practices for prevention of central line associated bloodstream infections Study (CHanGing BathS): a stepped wedge cluster randomized trial. Implement Sci. 2021 Apr 26;16(1):45. doi: 10.1186/s13012-021-01112-4. [Accessed 27 Jun. 2024] Available at: