Secrin R Tablet

Introduction

Secrin R is a prescription medication that combines three active ingredients: Glibenclamide, Metformin, and Pioglitazone. It is commonly used in the treatment of type 2 diabetes mellitus. Secrin R helps control blood sugar levels by improving insulin secretion, reducing insulin resistance, and decreasing glucose production in the liver.

Uses

Secrin R is primarily prescribed for the management of type 2 diabetes mellitus. It is used to help lower blood sugar levels in individuals with this condition. Note that Secrin R is not a substitute for a healthy lifestyle, including regular exercise and a balanced diet. It should be used in conjunction with these lifestyle modifications as recommended by your healthcare provider.

Dosage and Administration

The dosage of Secrin R will vary depending on individual factors such as your age, medical history, and response to treatment. Follow your healthcare provider’s instructions regarding the exact dosage and duration of treatment. Typically, the recommended starting dose for adults is one tablet taken orally once daily with meals. Your healthcare provider may adjust the dose as needed to achieve optimal blood sugar control.

Mechanism of Action

Secrin R contains three active ingredients that work together to control blood sugar levels. Glibenclamide stimulates the release of insulin from the pancreas, helping to lower blood sugar levels. Metformin reduces the production of glucose in the liver and improves insulin sensitivity, allowing for more efficient use of insulin in the body. Pioglitazone helps reduce insulin resistance, allowing insulin to work more effectively in lowering blood sugar levels.

Side Effects

Common side effects may include nausea, diarrhea, stomach upset, headache, and dizziness. These side effects are usually mild and temporary. However, if they persist or become bothersome, consult your healthcare provider.

In rare cases, Secrin R may cause serious side effects such as hypoglycemia (low blood sugar), allergic reactions, liver problems, and heart failure. If you experience any symptoms of hypoglycemia (such as sweating, trembling, confusion, or blurred vision), seek immediate medical attention. Report any signs of allergic reactions, liver problems, or heart failure to your healthcare provider.

Drug Interactions

Secrin R may interact with other medications and substances. Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Certain medications, such as certain antibiotics or antifungal agents, may interact with Secrin R and affect its effectiveness or increase the risk of side effects. Your healthcare provider will be able to determine if any adjustments to your medication regimen are necessary.

Precautions

Before starting Secrin R, inform your healthcare provider about any medical conditions you have, especially if you have a history of liver or kidney problems, heart disease, or any other significant medical condition. Secrin R may not be suitable for everyone, and your healthcare provider will consider these factors before prescribing the medication.

Secrin R should be used with caution in individuals who are pregnant, planning to become pregnant, or breastfeeding. Discuss the potential risks and benefits with your healthcare provider in these situations.

Storage

Secrin R should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Take Secrin R exactly as prescribed by your healthcare provider. Do not adjust the dosage or stop taking the medication without consulting your healthcare provider.
• Follow a healthy lifestyle that includes regular exercise and a balanced diet to complement the effects of Secrin R in managing your blood sugar levels.
• Monitor your blood sugar levels regularly as directed by your healthcare provider.
• attend regular check-ups with your healthcare provider to monitor your response to Secrin R and make any necessary adjustments to your treatment plan.
• If you have any questions or concerns about Secrin R or your diabetes management, do not hesitate to consult your healthcare provider. They are there to support you and provide guidance throughout your treatment journey.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Metformin: a medicine to treat type 2 diabetes (NHS UK) [Accessed 10 Jun. 2024] (online) Available at:
• AMGLIDIA 0.6 mg/mL oral suspension with 5 mL oral syringe (Health Professionals SmPC) Available at:
• Glibenclamide (International database) (Drugs.com) [Accessed 19 Jun. 2024] (online) Available at:
• metformin (RX) [Accessed 21 Jun. 2024] (online) Available at:
• Glyburide (MedlinePlus) [Accessed 11 Jun. 2024] (online) Available at:
• Zubov A, Muruzheva Z, Tikhomirova M, Karpenko M. Glibenclamide as a neuroprotective antidementia drug. Arch Physiol Biochem. 2022 Dec;128(6):1693-1696. doi: 10.1080/13813455.2020.1789170. Epub 2020 Jul 11. [Accessed 3 Jun. 2024] Available at: