Sevincio Tablet

Introduction

Sevincio is a prescription medication that contains the active ingredient Sevelamer. It is commonly prescribed under the brand name Sevincio.

Uses

Sevincio is primarily used to lower blood phosphate levels in patients with chronic kidney disease (CKD) who are on dialysis. It works by binding to phosphate in the diet and preventing its absorption in the body. By reducing phosphate levels, Sevincio helps to maintain the balance of minerals in the blood and prevent complications associated with high phosphate levels, such as bone problems.

Dosage and Administration

The dosage of Sevincio will vary depending on individual patient characteristics and the specific recommendations of the healthcare provider. Follow the prescribed dosage instructions carefully.

Sevincio is usually taken orally with meals. Swallow the tablet whole and not crush or chew it. Drink plenty of fluids while taking this medication to ensure proper hydration and to help prevent constipation.

Mechanism of Action

Sevelamer, the active ingredient in Sevincio, is a phosphate binder. It works by binding to phosphate in the gastrointestinal tract and preventing its absorption into the bloodstream. By reducing the absorption of phosphate, Sevincio helps to lower blood phosphate levels and maintain the balance of minerals in the body.

Side Effects

Common side effects may include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and abdominal pain. These side effects are usually mild and may improve over time.

Serious side effects are rare but can occur. These may include severe allergic reactions, difficulty swallowing, or symptoms of low calcium levels such as muscle spasms or tingling sensations. If any of these serious side effects occur, seek medical attention immediately.

Drug Interactions

Sevincio may interact with other medications. Inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal products. Some medications, such as certain antibiotics, may reduce the effectiveness of Sevincio. Your healthcare provider will advise you on any necessary dosage adjustments or potential drug interactions.

Precautions

Before taking Sevincio, inform your healthcare provider about any allergies or medical conditions you have, especially if you have a history of bowel obstruction or gastrointestinal motility disorders. Sevincio may not be suitable for everyone, and your healthcare provider will assess the risks and benefits before prescribing it to you.

Avoid taking other medications, including antacids or certain laxatives, within a few hours of taking Sevincio, as they may interfere with its absorption.

Storage

Sevincio should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use Sevincio after the expiration date printed on the packaging.

Patient Tips

• Take Sevincio exactly as prescribed by your healthcare provider. Do not change the dosage or stop taking it without consulting your healthcare provider.
• Remember to take Sevincio with meals and drink plenty of fluids to help prevent constipation.
• If you experience any bothersome or persistent side effects, consult your healthcare provider for further guidance.
• Inform your healthcare provider about all the medications you are taking, including over-the-counter and herbal products, to avoid potential drug interactions.
• Store Sevincio in a cool, dry place and keep it out of reach of children and pets.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Renagel 800 mg film-coated tablets (Health Professionals SmPC) Available at:
• Sevelamer (Drugs.com) [Accessed 12 Jun. 2024] (online) Available at:
• sevelamer (RX) [Accessed 29 Jun. 2024] (online) Available at:
• Sevelamer (MedlinePlus) [Accessed 17 Jun. 2024] (online) Available at:
• Barna MM, Kapoian T, O’Mara NB. Sevelamer carbonate. Ann Pharmacother. 2010 Jan;44(1):127-34. doi: 10.1345/aph.1M291. Epub 2009 Dec 2. [Accessed 13 Jun. 2024] Available at: