Introduction
Shiloxa is a prescription medication that contains the active ingredient Oxaceprol. It is available in capsule form and is commonly prescribed by healthcare professionals.
Uses
Shiloxa is primarily used to provide relief from symptoms associated with osteoarthritis. It is prescribed to help reduce pain, inflammation, and stiffness in the joints caused by this condition.
Dosage and Administration
When taking Shiloxa, follow the instructions provided by your healthcare professional. The dosage may vary depending on the severity of your symptoms and your individual medical condition. Typically, the recommended dosage is 1 capsule taken orally twice a day, preferably with meals. Swallow the capsule whole with a glass of water and not to crush or chew it.
Mechanism of Action
Shiloxa works by inhibiting the production of certain substances in the body that contribute to inflammation and pain. Oxaceprol, the active ingredient in this medication, helps to reduce the production of inflammatory cytokines, which are responsible for the inflammatory response in osteoarthritis. By reducing inflammation, Shiloxa can help alleviate the symptoms associated with this condition.
Side Effects
Common side effects that have been reported include nausea, abdominal discomfort, and diarrhea. These side effects are usually mild and temporary, but if they persist or worsen, consult your healthcare professional.
In rare cases, some individuals may experience more serious side effects such as allergic reactions, including rash, itching, swelling, dizziness, and difficulty breathing. If you experience any of these serious side effects, seek immediate medical attention.
Drug Interactions
Shiloxa may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. Inform your healthcare professional about all the medications, supplements, or herbal products you are currently taking before starting Shiloxa. Common drug interactions may occur with medications such as warfarin, aspirin, and other nonsteroidal anti-inflammatory drugs (NSAIDs). Your healthcare professional will be able to provide specific guidance on any potential drug interactions.
Precautions
Before taking Shiloxa, inform your healthcare professional about any allergies you may have, especially to medications containing Oxaceprol. Additionally, let your healthcare professional know about any other medical conditions you have, including kidney or liver disease. Disclose any medications or supplements you are currently taking to avoid potential interactions.
Shiloxa is not recommended for use during pregnancy or while breastfeeding. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of this medication with your healthcare professional.
Storage
Shiloxa should be stored at room temperature, away from moisture and heat. Keep the medication in its original packaging and out of reach of children. Do not use the medication if the packaging is damaged or if the expiration date has passed. If you have any unused or expired medication, consult your healthcare professional or pharmacist for proper disposal methods.
Patient Tips
- Take the medication exactly as prescribed by your healthcare professional.
- If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- Do not exceed the recommended dosage without consulting your healthcare professional.
- If you have any questions or concerns about your treatment, don’t hesitate to reach out to your healthcare professional for guidance.
- Keep a record of any side effects you may experience and discuss them with your healthcare professional during your follow-up appointments.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Alarçin E, Demirbağ Ç, Karsli-Ceppioglu S, Kerimoğlu O, Bal-Ozturk A. Development and characterization of oxaceprol-loaded poly-lactide-co-glycolide nanoparticles for the treatment of osteoarthritis. Drug Dev Res. 2020 Jun;81(4):501-510. doi: 10.1002/ddr.21642. Epub 2020 Jan 20. [Accessed 25 Jun. 2024] Available at:
- Herrmann G, Steeger D, Klasser M, Wirbitzky J, Fürst M, Venbrocks R, Rohde H, Jungmichel D, Hildebrandt HD, Parnham MJ, Gimbel W, Dirschedl H. Oxaceprol is a well-tolerated therapy for osteoarthritis with efficacy equivalent to diclofenac. Clin Rheumatol. 2000;19(2):99-104. doi: 10.1007/s100670050025. [Accessed 27 Jun. 2024] Available at:
- Mukhopadhyay K, Ghosh P, Ghorai P, Hazra A, Das AK. Oxaceprol versus tramadol for knee osteoarthritis: A randomized controlled trial. Indian J Pharmacol. 2018 Sep-Oct;50(5):266-272. doi: 10.4103/ijp.IJP_633_16. [Accessed 2 Jun. 2024] Available at:
- Durg S, Lobo M, Venkatachalam L, Rao G, Bhate J. A systematic review and meta-analysis of oxaceprol in the management of osteoarthritis: An evidence from randomized parallel-group controlled trials. Pharmacol Rep. 2019 Apr;71(2):374-383. doi: 10.1016/j.pharep.2018.12.010. Epub 2018 Dec 26. [Accessed 10 Jun. 2024] Available at:
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